Results 31 to 40 of about 263,263 (320)

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

The Scope of the Right to Health in International Human Rights Law [PDF]

open access: yesFaṣlnāmah-i Pizhūhish-i Huqūq-i ̒Umūmī, 2014
"The right to the enjoyment of the highest attainable standard of mental & physical health" is defined as a fundamental right which has critical important for the realization of the other rights. Belonged to the second generation of human rights, however,
Ehsan Javid, Saber Niavarani
doaj  

Contraction of Marriage in Traditional Judaism

open access: yesEdinost in Dialog, 2021
Nations and peoples throughout history have formulated norms that govern interpersonal relations. In this sense the Jewish Law is unique, as it is not a system of regulations of a state but of a people with more than 3000 years of history.
Andrej Saje
doaj   +1 more source

The Covenant Never Revoked: Biblical Reflections on a Christian-Jewish Dialogue [PDF]

open access: yes, 1994
Reviewed Book: Lohfink, Norbert. The Covenant Never Revoked: Biblical Reflections on a Christian-Jewish Dialogue.
Denef, Lawrence W.
core   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Jews, Gentiles, and “in Christ” Identity: A Post-Supersessionist Reading of Philippians

open access: yesReligions, 2023
Interpretations of Philippians have commonly suggested that the letter seeks to demonstrate the worthlessness of Paul’s own (former) Jewish identity, and thus that the Philippians should not be led astray by those who would persuade them to adopt the ...
Christopher Zoccali
doaj   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

Moraltheologischen implikationen des glaubens nach der apostolichen exhortation evangelii Gaudium des Papsted Franziskus

open access: yesColloquia Theologica Ottoniana, 2016
Pope Francis puts special emphasis in his teaching and pastoral activities on the need for evangelisation which is to awaken (reawaken) the readiness to revive the grace that flows out from the gift of faith being received.
Grzegorz Chojnacki
doaj   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

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