Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Cover Plants-Mediated Suppression of Fusarium Wilt and Root-Knot Incidence of Cucumber is Associated With the Changes of Rhizosphere Fungal Microbiome Structure-Under Plastic Shed System of North China. [PDF]
Ali A +6 more
europepmc +1 more source
Development and Monitoring of Revegetation Methods: Connecting Students with Restoration Activities at Awcomin Marsh [PDF]
Five classes in a local elementary school participated in an effort to grow and plant high marsh and upper border vegetation at a salt marsh restoration site in spring 2005.
Burdick, David M. +2 more
core +2 more sources
RIPK4 function interferes with melanoma cell adhesion and metastasis
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Effects of systemic and non-systemic stresses on the thermal characteristics of corn [PDF]
Experiments were conducted on corn plants using a calibrated spectroradiometer under field conditions in the indium antimonide channel (InSb, 2.8 to 5.6 mm) and the mercury cadmium telluride channel (HgCdTe, 7 to 14 mm).
Baer, M. E., Kumar, R., Silva, L. F.
core +1 more source
Tillage Radish Planting Date x Seeding Rate Trial [PDF]
Farmers are interested in growing tillage radishes as they may potentially offer many environmental and economic benefits. Tillage radishes are quick at scavenging excess nitrogen (N), provide good ground cover, and break down very quickly in the spring ...
Brigham, Nate +5 more
core +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Nutrient Trading, the Flush Tax, and Maryland's Nitrogen Emissions to the Chesapeake Bay [PDF]
We investigate nutrient trading for point and non-point sources for the Bay Restoration Fund in Maryland. We demonstrate how to use the proceeds from the tax revenue to mimic trading high-cost upgrades of sewage treatment plants for low-cost winter cover
Hanson, James C., McConnell, Kenneth E.
core +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Cover plants with potential use for crop-livestock integrated systems in the Cerrado region
The objective of this work was to evaluate the effects of lignin, hemicellulose, and cellulose concentrations in the decomposition process of cover plant residues with potential use in no-tillage with corn, for crop-livestock integrated system, in the ...
Arminda Moreira de Carvalho +4 more
doaj +1 more source

