Results 141 to 150 of about 4,443,351 (328)

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Job-based Coverage Drops for Adults and Children but Public Programs Boost Children's Coverage [PDF]

open access: yes, 2005
Provides a profile of non-elderly Californians' health insurance coverage and lack of coverage, and describes how these rates have changed. Estimates the number of children and adults who are uninsured but eligible for coverage through public ...
E. Richard Brown, Shana Alex Lavarreda
core  

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

open access: yesMolecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande   +11 more
wiley   +1 more source

One-Fifth of Nonelderly Californians Do Not Have Access to Job-Based Health Insurance Coverage [PDF]

open access: yes, 2010
Examines access to employer-based coverage among children and nonelderly adults age 64 and under, insurance status, and other sources of coverage, including Medi-Cal and family coverage, by income, firm size, citizenship, race/ethnicity, and ...
Livier Cabezas, Shana Alex Lavarreda
core  

Analyzing Subnational Immunization Coverage to Catch up and Reach the Unreached in Seven High-Priority Countries in the Eastern Mediterranean Region, 2019–2021

open access: yesVaccines
Yearly national immunization coverage reporting does not measure performance at the subnational level throughout the year and conceals inequalities within countries.
Kamal Fahmy   +3 more
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Medicare Prescription Drug Plans in 2008 and Key Changes Since 2006: Summary of Findings [PDF]

open access: yes, 2008
Synthesizes findings from prior research on the scope and generosity of drug coverage under Medicare Part D, as well as on changes in drug coverage and costs since 2006.
Elizabeth Hargrave   +3 more
core  

Screening for lung cancer: A systematic review of overdiagnosis and its implications

open access: yesMolecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz   +12 more
wiley   +1 more source

Secrecy coverage [PDF]

open access: yes2010 Conference Record of the Forty Fourth Asilomar Conference on Signals, Systems and Computers, 2010
Amites Sarkar, Martin Haenggi
openaire   +1 more source

The Medicare Part D Coverage Gap: Costs and Consequences in 2007 [PDF]

open access: yes, 2008
Analyzes data on Medicare Part D enrollees who reached the coverage gap and had to pay the full cost until they qualified for catastrophic coverage, who then stopped taking their medications or bought cheaper ones, and who received catastrophic ...
Elizabeth Hargrave   +3 more
core  

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