Results 61 to 70 of about 862,801 (304)

Multi-User Coverage Probability of Uplink Cellular Systems: a Stochastic Geometry Approach

, 2014
We analyze the coverage probability of multi-user uplink cellular networks with fractional power control. We use a stochastic geometry approach where the mobile users are distributed as a Poisson Point Process (PPP), whereas the serving base station (BS)
Aguayo-Torres, Mari Carmen, Gomez, Gerardo, Lopez-Martinez, F. Javier, Martin-Vega, F. Javier   +3 more
core   +1 more source

Ergothioneine supplementation improves pup phenotype and survival in a murine model of spinal muscular atrophy

FEBS Letters, EarlyView.
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile, Daniela Ratto, Giorgia Rastelli, Ottavia Eleonora Ferraro, Caterina Temporini, Sunil Kumar, Simona Boncompagni, Paola Rossi, Monica Canepari   +8 more
wiley   +1 more source

Confidence interval estimation for vaccine efficacy against COVID-19

Frontiers in Public Health, 2022
This article focuses on the construction of a confidence interval for vaccine efficacy against contagious coronavirus disease-2019 (COVID-19) in a fixed number of events design.
Qinyu Wei, Peng Wang, Ping Yin
doaj   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

Generalized Confidence Intervals for Zero-Inflated Pareto Distribution

Mathematics, 2021
This paper considers interval estimations for the mean of Pareto distribution with excess zeros. Three approaches for interval estimation are proposed based on fiducial generalized pivotal quantities (FGPQs), respectively.
Xiao Wang, Xinmin Li
doaj   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

Generalized confidence interval for the common coefficient of variation of several zero-inflated Birnbaum-Saunders distributions with an application to wind speed data

AIMS Mathematics
Wind speed is a critical factor that affects various aspects of life in Thailand, particularly agriculture, which is a fundamental component of the Thai economy.
Usanee Janthasuwan, Suparat Niwitpong, Sa-Aat Niwitpong   +2 more
doaj   +1 more source

Analysis of Load Balancing and Interference Management in Heterogeneous Cellular Networks

IEEE Access, 2017
To meet the current cellular capacity demands, proactive offloading is required in heterogeneous cellular networks (HetCNets) comprising of different tiers of base stations (BSs), e.g., small-cell BSs (sBSs) and conventional macro-cell BSs (mBSs).
Ziaul Haq Abbas, Fazal Muhammad, Lei Jiao   +2 more
doaj   +1 more source

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias, Ana Oitabén, Sonia Zumalave, Bernardo Rodriguez‐Martin, María Gallardo‐Gómez, Martín Santamarina, Ana Pequeño‐Valtierra, Laura Juaneda‐Magdalena, Ramón García‐Escudero, José Luis López‐Cedrún, Máximo Fraga, José M. C. Tubio, Mónica Martínez‐Fernández   +12 more
wiley   +1 more source

Multi-Connectivity Between Terrestrial and Non-Terrestrial MIMO Systems

IEEE Open Journal of the Communications Society
Communicating in a non-terrestrial network (NTN) has recently emerged as a promising technology to provide global seamless connectivity. Although low earth orbit (LEO) satellites in an NTN have been employed for providing ubiquitous coverage and high ...
Bodong Shang, Xiangyu Li, Zhuhang Li, Junchao Ma, Xiaoli Chu, Pingzhi Fan   +5 more
doaj   +1 more source