Results 41 to 50 of about 5,535 (255)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Covert Channel Detection: Machine Learning Approaches

open access: yesIEEE Access, 2022
The advanced development of computer networks and communication technologies has made covert communications easier to construct, faster, undetectable and more secure than ever.
Muawia A. Elsadig, Ahmed Gafar
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Practical covert channels for WiFi systems [PDF]

open access: yes2015 IEEE Conference on Communications and Network Security (CNS), 2015
Wireless covert channels promise to exfiltrate information with high bandwidth by circumventing traditional access control mechanisms. Ideally, they are only accessible by the intended recipient and---for regular system users/operators---indistinguishable from normal operation.
Jiska Classen   +2 more
openaire   +2 more sources

Identification of DNS covert channel based on improved convolutional neural network

open access: yesTongxin xuebao, 2020
In order to effectively identify the multiple types of DNS covert channels,the implementation of different sorts of DNS covert channel software was studied,and a detection based on the improved convolutional neural network was proposed.The experimental ...
Meng ZHANG, Haoliang SUN, Peng YANG
doaj   +2 more sources

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Covert communications on Poisson packet channels [PDF]

open access: yes2015 53rd Annual Allerton Conference on Communication, Control, and Computing (Allerton), 2015
Allerton 2015 submission, minor edits ...
Ramin Soltani   +3 more
openaire   +2 more sources

A Formulation of the Potential for Communication Condition using C2KA [PDF]

open access: yesElectronic Proceedings in Theoretical Computer Science, 2014
An integral part of safeguarding systems of communicating agents from covert channel communication is having the ability to identify when a covert channel may exist in a given system and which agents are more prone to covert channels than others. In this
Jason Jaskolka, Ridha Khedri
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

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