Results 131 to 140 of about 4,658,543 (286)

mGluR5 in ECCCK to BLA Circuit Modulates Depressive‐Like Phenotypes through CCK Signaling

open access: yesAdvanced Science, EarlyView.
Dysregulation of mGluR5 and CCK signaling contributes to major depressive disorder, yet circuit‐level mechanisms remain unclear. Here, the ECCCK→BLA pathway is identified as a critical regulator of affective behavior. mGluR5 modulates synaptic function and CCK signaling within this circuit, controlling stress susceptibility and depressive‐like states ...
Muhammad Asim   +4 more
wiley   +1 more source

Underlying medical conditions and people at higher risk for coronavirus disease 2019 (COVID-19) [PDF]

open access: yes
Date: Friday, March 27, 2020Time: 2:00\u20133:00 P.M. ETDuring this COCA call, presenters will focus on current information about people who are higher risk for COVID-19 complications because of their age or underlying medical conditions, particularly ...

core  

Cross‐Modal Denoising and Integration of Spatial Multi‐Omics Data with CANDIES

open access: yesAdvanced Science, EarlyView.
In this paper, we introduce CANDIES, which leverages a conditional diffusion model and contrastive learning to effectively denoise and integrate spatial multi‐omics data. We conduct extensive evaluations on diverse synthetic and real datasets, CANDIES shows superior performance on various downstream tasks, including denoising, spatial domain ...
Ye Liu   +5 more
wiley   +1 more source

COVID-19 state of vaccine confidence insights report : Updated (bivalent) COVID-19 booster dose report

open access: yes
Date Range: August 30 \u2013 September 12, 2022Summary of the 2nd COVID-19 Vaccine Summary Report: 6 months through 5 yearsThis report consolidates findings and ways public health partners can act on the findings related to COVID-19 vaccines for children

core  

Gasdermin D‐Mediated Release of IL‐33 Results in Fetal Brain Developmental Abnormalities During Maternal Colitis

open access: yesAdvanced Science, EarlyView.
Under colitis, Gsdmd mediates the release of IL‐33 from the epithelium of pregnant mice. IL‐33 can cross the placenta and enhance the proliferative capacity of neural stem cells, ultimately resulting in behavioral deficits in the offspring. Excessive pyroptosis in the colonic epithelium also triggers the translocation of LPS, which in turn increases ...
Huiyang Jia   +4 more
wiley   +1 more source

COVID-19 science update ; Edition 2021-11-19 (114)

open access: yes
The COVID-19 Science Update summarizes new and emerging scientific data for public health professionals to meet the challenges of this fast-moving pandemic. Weekly, staff from the CDC COVID-19 Response and the CDC Library systematically review literature

core  

National Forum on COVID-19 Vaccine : overview [PDF]

open access: yes
The National Forum on COVID-19 Vaccine is a 3-day virtual event bringing together COVID-19 vaccine practitioners and champions from across the country to exchange information, strategies, and promising practices for effective and equitable vaccine ...

core  

COVID-19: the lessons [PDF]

open access: yesBritish Journal of Healthcare Management, 2020
McIntosh, B, Bromley, J
openaire   +2 more sources

Multidimensional and Multifunctional Laser‐Induced Graphene (LIG) for Point‐of‐Care and Wearable Biosensing, Theranostics, and Bioactive Interfaces Toward Personalized Healthcare and Regenerative Medicine

open access: yesAdvanced Science, EarlyView.
Multidimensional laser‐induced graphene (LIG) spanning from 0D to 3D architectures is comprehensively reviewed for multifunctional biomedical platforms, including biosensing, theranostics, and bioactive interface applications, which highlights its potentials for point‐of‐care diagnostics, wearable health monitoring, smart drug delivery, and tissue ...
Li Zhang   +3 more
wiley   +1 more source

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