Results 171 to 180 of about 4,921,923 (306)

Transdermal Delivery of an mRNA‐Liposome Vaccine via Dissolving Microneedle to Preserve Vaccine Activity and Enhance Immune Activation

Advanced Science, EarlyView.
An mRNA‐liposome vaccine via dissolving microneedles (ML‐DMN) enables efficient skin‐targeted delivery while preserving mRNA integrity and allowing sustained antigen expression. Unlike intramuscular (IM) injection, ML‐DMN engages skin‐resident immune cells, activates antigen‐presenting cells (APCs), and induces strong T cell and cytokine responses at ...
Jeehye Nam, JiWon Ahn, Jiwoo Shin, Nahong Lee, Youjin Lee, Sung min Cho, Paul Kim, Geonwoo Kang, Sang‐Jun Ha, Hyungil Jung   +9 more
wiley   +1 more source

Maßnahmen zur vierten COVID-19-Welle und zur neuen SARS-Coronavirus-Variante "Omikron"

, 2021
Viola Priesemann, Eva Grill, Emil N. Iftekhar, Christian Karagiannidis, André Karch, Mirjam Kretzschmar, Berit Lange, Kai Nagel, Armin Nassehi, Mathias W. Pletz, Ulrike Protzer, Anita Schöbel, Andreas Schuppert, Klaus Überla, Hajo Zeeb   +14 more
openalex   +2 more sources

COVID-19 RESOURCES [PDF]

, 2020
Institute for Health Policy and Practice, Porter, Josephine B.   +1 more
core   +1 more source

Mass‐Produced and High‐Performance Nanowell Biosensor Fabricated via Semiconductor Manufacturing for Rapid and Accurate COVID‐19 Diagnosis in the Clinical Field

Advanced Science, EarlyView.
A semiconductor‐fabricated nanowell biosensor enables rapid, scalable, and highly reproducible detection of SARS‐CoV‐2 antigens from nasal swabs within ∼10 minutes. Clinical validation in 249 retrospective and 243 prospective patient samples demonstrates high sensitivity and specificity, minimal cross‐reactivity, and robust batch‐to‐batch ...
Yoo Min Park, Zahra Rezaei, Nam Ho Bae, Donggee Rho, Da‐Seul Kim, EunYoung Go, YoungTae Seo, Seok Jae Lee, Won Chan Seo, Luke P. Lee, HeaYeon Lee, Su Ryon Shin   +11 more
wiley   +1 more source

Peer Review #2 of "Characteristics of patients discontinuing outpatient services under long-term care insurance and its effect on frailty during COVID-19 (v0.2)"

, 2021

openalex   +1 more source

COVID-19 remedies [PDF]

Nature Biomedical Engineering, 2020
openaire   +2 more sources

Multimodal Wearable Biosensing Meets Multidomain AI: A Pathway to Decentralized Healthcare

Advanced Science, EarlyView.
Multimodal biosensing meets multidomain AI. Wearable biosensors capture complementary biochemical and physiological signals, while cross‐device, population‐aware learning aligns noisy, heterogeneous streams. This Review distills key sensing modalities, fusion and calibration strategies, and privacy‐preserving deployment pathways that transform ...
Chenshu Liu, Haolin Fan, Minwoo Kim, Tong Zhou, Pinyi Yang, Lingdi Zhao, Yiran Wang, Ziyuan Che, Chia‐Wei Liu, Bingbing Li, Yangzhi Zhu   +10 more
wiley   +1 more source

mGluR5 in ECCCK to BLA Circuit Modulates Depressive‐Like Phenotypes through CCK Signaling

Advanced Science, EarlyView.
Dysregulation of mGluR5 and CCK signaling contributes to major depressive disorder, yet circuit‐level mechanisms remain unclear. Here, the ECCCK→BLA pathway is identified as a critical regulator of affective behavior. mGluR5 modulates synaptic function and CCK signaling within this circuit, controlling stress susceptibility and depressive‐like states ...
Muhammad Asim, Huajie Wang, Gao Qianqian, Abdul Waris, Jufang He   +4 more
wiley   +1 more source

Transcriptomics of severe COVID-19. [PDF]

Vavilovskii Zhurnal Genet Selektsii
Gusarova AA, Trifonova EA, Babovskaya AA, Gavrilenko MM, Stepanov VA.   +4 more
europepmc   +1 more source

Peer Review #1 of "Time series data analysis and ARIMA modeling to forecast the short-term trajectory of the acceleration of fatalities in Brazil caused by the corona virus (COVID-19) (v0.2)"

, 2021
Vrijesh Tripathi, Akini James, J Carcione, J Santos, C Bagaini, J Ba, C Chan, Gch Chan, T Leeper, J Becker, X Chen, B Yu, R Cleveland, W Cleveland, J Mcrae, I Terpenning, N Cohn, J Katz, M Sanger-Katz, K Quealy, E Dong, H Du, L Gardener, C Feng, H Wang, N Lu, T Chen, H He, Y Lu, X Tu, M Gardener, R Hyndman, R Hyndman, G Athanasopoulos, C Bergmeir, G Caceres, L Chhay, O 'hara-Wild, M Petropoulos, F Razbash, S Wang, E Yasmeen, F, R Hyndman, Y Khandakar, Adrian Trapletti, Kurt Hornik, A Keshvani, K Mclaughlin, R Nau, D Nykamp, K Roosa, Y Lee, R Luo, A Kirpich, R Rothenberg, J Hayman, P Yan, G Chowell, F Taspinar, N Celebi, N Tutkun, Y Utsunomiya, Ath Utsunomiya, Rbp Torrechilha, S Paulan, M Milanesi, J Garcia, A Veloso, N Ziviani, H Wickham, M Averick, J Bryan, W Chang, L Mcgowan, R Franois, G Grolemund, A Hayes, L Henry, J Hester, M Kuhn, T Pedersen, E Miller, S Bache, K Mller, J Ooms14, D Robinson, D Seidel, V Spinu, K Takahashi, D Vaughan, C Wilke, K Woo, H Yutani, Worldometer   +94 more
openalex   +2 more sources