Results 231 to 240 of about 1,987,016 (297)

Refractory Status Epilepticus and Therapeutic Uncertainties: a Comprehensive Review on Targeting Neuroinflammation and Rationale for Developing a Platform Trial

Advanced Science, EarlyView.
Refractory status epilepticus (RSE) is a life‐threatening neurological emergency with high rates of death and long‐term disability, but treatments for it are often based on limited evidence. RSE is now understood to involve neuroinflammation, which has led to the exploration of anti‐inflammatory and immunomodulatory agents like Tocilizumab. Traditional
Shanika Samarasekera, Suneesh Thilak, Asha Patel, Prashant Nasa, Zubair Ahmed, Lorraine Jacques, William J. Scotton, Cyril Chacko, Randeep Mullhi, Ruoling Chen, Vikram Patil, Suresh Renukappa, Tonny Veenith   +12 more
wiley   +1 more source

SERVIÇO EM ABA PARA INDIVÍDUOS COM TEA: CONTINUAR O SERVIÇO PRESENCIAL EM TEMPOS DE COVID-19?

, 2019
Daniela de Souza Canovas, Maria Tereza Monteiro da Cruz, Maria America Coimbra De Andrade   +2 more
openalex   +1 more source

Effect of Preinfection Health Status on COVID-19 Severity and Cognitive Function. [PDF]

Brain Behav
Yuan K, Xian W, Lin L, Su F, Huang F, Sheng W, Wu W.   +6 more
europepmc   +1 more source

An Aptamer‐Based EXACT Anticoagulant as a Sustainable, Animal‐Free Alternative to Unfractionated Heparin

Advanced Science, EarlyView.
By simply conjugating thrombin's active‐site inhibitor, dabigatran, with an exosite inhibitor, aptamer HD1, the resulting EXosite‐ACTive site (EXACT) inhibitors show two orders of magnitude higher potency and selectivity via synergistic binding, while maintaining the aptamer's antidote‐reversible trait, yielding a potential substitute for the animal ...
Haixiang Yu, George Pitoc, Manqi Zhang, Jeffrey Clancy, James Frederiksen, Amy Yan, Samuel Francis, Rebecca Sullenger, Rachel Rempel, Susannah Gammell, Jillian Caiazzi, Bruce A. Sullenger   +11 more
wiley   +1 more source

COVID-19 among cancer patients. What we know so far?

, 2019
Renata D’Alpino Peixoto, Moises de Sousa Martins Lopes   +1 more
openalex   +1 more source

Family communication and child behavior problems during the COVID-19 pandemic. [PDF]

Dev Psychol
Lamoreau R, Wilson A, Pequet A, Skov H, Gray SAO.   +4 more
europepmc   +1 more source

High‐Throughput Strategies for Streamlining Lipid Nanoparticle Development Pipeline

Advanced Science, EarlyView.
This review highlights emerging state‐of‐the‐art high‐throughput strategies for optimising lipid nanoparticle formulation. By integrating combinatorial design, characterization, in vitro/in vivo screening, automation, and machine learning into a closed‐loop framework, it provides a roadmap to streamline discovery and accelerate the translation of ...
Lois Lam, Stephanie Watson, Yogambha Ramaswamy, Gurvinder Singh   +3 more
wiley   +1 more source

Spontaneous Pneumomediastinum in a Patient With Severe COVID-19 Pneumonia: A Case Report. [PDF]

Clin Case Rep
Mulisa MD, Tasamma AT, Mulate ST, Azerefegne EF.   +3 more
europepmc   +1 more source

Unveiling Novel Viral Diversity, Biogeography, and Host Networks in Wildlife Through High‐Throughput Sequencing Data Mining

Advanced Science, EarlyView.
Analysis of 57 536 high‐throughput sequencing datasets uncovers a vast, hidden world of viruses in wildlife. The researchers reveal significant geographic and host‐specific patterns of viruses, and their surprising cross‐species transmissions, such as avian flu viruses infecting goats.
Hai Wang, Yafei Meng, Xiaoyuan Chen, Xinyuan Cui, Qian Zuo, Na Han, Xianghui Liang, Xuejuan Shen, Caiwu Li, Desheng Li, Fumin Wang, Liangping He, Rujian Chen, Xingbang Lu, Wenjie You, Aiping Wu, Rui‐Ai Chen, Wu Chen, Chan Ding, Yongyi Shen   +19 more
wiley   +1 more source

Psicanálise aplicada ao contexto hospitalar: intervenções em tempos de pandemia Covid-19

, 2019
Fernanda Saboya R. Almendra, Tânia Coelho dos Santos, Manuella Itapary Ribeiro Moreira, Maria Gabriela Castro   +3 more
openalex   +1 more source