Results 51 to 60 of about 64,190,465 (252)

Intensive diagnostic management of coronavirus disease 2019 (COVID-19) in academic settings in Japan: challenge and future

Inflammation and Regeneration, 2020
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), first emerged in Wuhan, China, and has spread globally to most countries. In Japan, the first COVID-19 patient was identified on January 15, 2020.
Tokio Hoshina, Hiroka Aonuma, Manabu Ote, Tatsuya Sakurai, Erisha Saiki, Yuki Kinjo, Kazuhiro Kondo, Masataka Okabe, Hirotaka Kanuka   +8 more
doaj   +1 more source

Quantitative comparison of SARS-CoV-2 nucleic acid amplification test and antigen testing algorithms: a decision analysis simulation model

BMC Public Health, 2022
Background Antigen tests for SARS-CoV-2 offer advantages over nucleic acid amplification tests (NAATs, such as RT-PCR), including lower cost and rapid return of results, but show reduced sensitivity.
Phillip P. Salvatore, Melisa M. Shah, Laura Ford, Augustina Delaney, Christopher H. Hsu, Jacqueline E. Tate, Hannah L. Kirking   +6 more
doaj   +1 more source

Acceptability and feasibility of strategies to shield the vulnerable during the COVID-19 outbreak: a qualitative study in six Sudanese communities

BMC Public Health, 2021
Background Shielding of high-risk groups from coronavirus disease (COVID-19) has been suggested as a realistic alternative to severe movement restrictions during the COVID-19 epidemic in low-income countries. The intervention entails the establishment of
Nada Abdelmagid, Salma A. E. Ahmed, Nazik Nurelhuda, Israa Zainalabdeen, Aljaile Ahmed, Mahmoud Ali Fadlallah, Maysoon Dahab   +6 more
doaj   +1 more source

Clinical characteristics of patients with COVID-19 admitted to the COVID-19 Emergency Field Hospital of Bangkalan, Indonesia [version 2; peer review: 2 approved]

F1000Research, 2022
Background: Following the surge of coronavirus disease 2019 (COVID-19) cases in the epicenter of East Java Province, this study aimed to determine the clinical characteristics of patients with COVID-19 at one of the emergency field hospitals in Indonesia.
Ahmad Maulana Ifan Akbas, Nathania Djaja, Perthdyatama Syifaq Budiono, Kurnia Auliyana Ar-Rahmah, Erwin Astha Triyono, Fenska Seipalla, Yussika Fernanda, Aditya Putra Pamungkas, Clarissa Azalia Maheswari, Alfin Jam'Annuri   +9 more
doaj   +1 more source

Procalcitonin as a Predictive Factor for the Clinical Outcome of Patients with Coronavirus Disease 2019 [PDF]

Journal of Acute Care Surgery, 2022
Purpose The coronavirus disease 2019 (COVID-19) pandemic continues. It has been reported that patients with bacterial coinfection have a higher mortality rate than patients without coinfection.
Sungho Lee, Jung Mo Lee, Taeyang Choi, Kwanhoon Park, Kang Yoon Lee, Ji young Jang   +5 more
doaj   +1 more source

A Randomized Placebo-Controlled Trial of Sarilumab in Hospitalized Patients with Covid-19

, 2021
BACKGROUND: Sarilumab (anti-interleukin-6 receptor-α monoclonal antibody) may attenuate the inflammatory response in Covid-19. METHODS: We performed an adaptive, phase 2/3, randomized, double-blind, placebo-controlled trial of intravenous sarilumab 200 ...
DiCioccio, A. Thomas, Saggar, Suraj, Sivapalasingam, Sumathi, Aberg, Judith A., Kampman, Wendy, Ferreira, Manuel A., Kosmicki, Jack A., Parrino, Jani, Boyapati, Anita, Criner, Gerard, Hosain, Romana, Labriola-Tompkins, Emily, Akinlade, Bolanle, Brown, Samuel M., Weinreich, David M., Bhore, Rafia, Ng Gong, Michelle, Horowitz, Julie E., Hajizadeh, Negin, Sobieszczyk, Magdalena E., Park, William, Gulabani, Daya, Yancopoulos, George D., Mahmood, Adnan, Lederer, David J., Sperber, Steven J., Musser, Bret, Stein, David K., Baras, Aris, Giannelou, Angeliki, Menon, Vidya, Somersan-Karakaya, Selin, O’Brien, Meagan, Purcell, Lisa A., Nivens, Michael C., Herman, Gary, Kowal, Bari, Waldron, Alpana, Braunstein, Ned, Ramesh, Divya   +39 more
core   +1 more source

Sex Differences in Use of Low Tidal Volume Ventilation in COVID-19—Insights From the PRoVENT–COVID Study [PDF]

, 2022
The purpose of this study was to compare and understand differences in the use of low tidal volume ventilation (LTVV) between females and males with acute respiratory distress syndrome (ARDS) related to coronavirus disease 2019 (COVID-19). This is a post-
Frederique Paulus, Neto, Ary Serpa, ‘PRactice of VENTilation in COVID-19’ (PRoVENT-COVID) Collaborative Group, Paulus, Frederique, Nijbroek, Sunny G. L. H., Schultz, Marcus J., Sunny G. L. H. Nijbroek, Ary Serpa Neto, Pien Swart, Marcus J. Schultz, Swart, Pien   +10 more
core   +2 more sources

Corticosteroid therapy in patients with heart failure hospitalized for COVID-19: a multicenter retrospective study. [PDF]

, 2021
The efficacy of corticosteroid use in COVID-19 has been widely debated [1]. Although corticosteroids were found to be associated with improved clinical outcomes in severely ill patients in a recent systematic review and meta-analysis of randomized ...
Sanz-Canovas, Jaime, Perez-Belmonte, Luis M, Salinas, Alejandro, Gomez-Huelgas, Ricardo, SEMI-COVID-19 Network, Fornie, Iñigo Sagastagoitia, Sagastagoitia-Fornie, Iñigo, Mendez-Bailon, Manuel   +7 more
core   +1 more source

Emergence and expansion of highly infectious spike protein D614G mutant SARS-CoV-2 in central India

Scientific Reports, 2021
COVID-19 has emerged as global pandemic with largest damage to the public health, economy and human psyche.The genome sequence data obtained during the ongoing pandemic are valuable to understand the virus evolutionary patterns and spread across the ...
Shashi Sharma, Paban Kumar Dash, Sushil Kumar Sharma, Ambuj Srivastava, Jyoti S. Kumar, B. S. Karothia, K. T. Chelvam, Sandeep Singh, Abhaydeep Gupta, Ram Govind Yadav, Ruchi Yadav, T. S. Greeshma, Pramod Kumar Kushwaha, Ravi Bhushan Kumar, D. P. Nagar, Manvendra Nandan, Subodh Kumar, Duraipandian Thavaselvam, Devendra Kumar Dubey   +18 more
doaj   +1 more source

Etoposide as Salvage Therapy for Cytokine Storm due to COVID-19

, 2020
Coronavirus disease 2019 (COVID-19) has resulted in significant morbidity and mortality because of a lack of effective therapies. Therapeutic strategies under investigation target the overactive cytokine response with anti-cytokine or immunomodulators ...
Bromberg, Michael, Criner, Gerard J., 0000-0002-1828-6524, 0000-0003-2402-1351, Caricchio, Roberto, Patel, Maulin, Sacher, Daniel, Desai, Parag, Chandar, Ashwin, Dominguez Castillo, Eduardo, 0000-0002-1379-1118   +10 more
core   +1 more source