Results 1 to 10 of about 7,455,591 (355)

Remdesivir for the Treatment of Covid-19 — Final Report

New England Journal of Medicine, 2020
Background Although several therapeutic agents have been evaluated for the treatment of coronavirus disease 2019 (Covid-19), no antiviral agents have yet been shown to be efficacious.
J. Beigel, K. Tomashek, L. Dodd, A. Mehta, B. Zingman, A. Kalil, E. Hohmann, H. Chu, A. Luetkemeyer, S. Kline, Diego López de Castilla, R. Finberg, K. Dierberg, V. Tapson, L. Hsieh, T. Patterson, R. Paredes, D. Sweeney, W. Short, G. Touloumi, D. Lye, N. Ohmagari, M. Oh, G. Ruiz-Palacios, T. Benfield, G. Fätkenheuer, M. Kortepeter, R. Atmar, C. Creech, J. Lundgren, A. Babiker, S. Pett, J. Neaton, T. Burgess, Tyler Bonnett, Michelle Green, M. Makowski, A. Osinusi, S. Nayak, H. Lane   +39 more
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Pulmonary Vascular Endothelialitis, Thrombosis, and Angiogenesis in Covid-19.

New England Journal of Medicine, 2020
BACKGROUND Progressive respiratory failure is the primary cause of death in the coronavirus disease 2019 (Covid-19) pandemic. Despite widespread interest in the pathophysiology of the disease, relatively little is known about the associated morphologic ...
M. Ackermann, S. Verleden, M. Kuehnel, A. Haverich, T. Welte, F. Laenger, A. Vanstapel, C. Werlein, Helge Stark, A. Tzankov, William Li, V. Li, S. Mentzer, D. Jonigk   +13 more
semanticscholar   +1 more source

Evaluation of science advice during the COVID-19 pandemic in Sweden

Humanities & Social Sciences Communications, 2022
Sweden was well equipped to prevent the pandemic of COVID-19 from becoming serious. Over 280 years of collaboration between political bodies, authorities, and the scientific community had yielded many successes in preventive medicine. Sweden’s population
Nele Brusselaers, David Steadson, Kelly Bjorklund, Sofia Breland, Jens Stilhoff Sörensen, Andrew Ewing, Sigurd Bergmann, Gunnar Steineck   +7 more
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Prevalence of risk behaviors and correlates of SARS-CoV-2 positivity among in-school contacts of confirmed cases in a Georgia school district in the pre-vaccine era, December 2020–January 2021

BMC Public Health, 2022
Background There is a continuing risk for COVID-19 transmission in school settings while transmission is ongoing in the community, particularly among unvaccinated populations. To ensure that schools continue to operate safely and to inform implementation
Marisa Hast, Megan Swanson, Colleen Scott, Emeka Oraka, Catherine Espinosa, Eleanor Burnett, Esther A. Kukielka, Marion E. Rice, Lemlem Mehari, Jazmyn McCloud, Danielle Miller, Rachel Franklin, Jacqueline E. Tate, Hannah L. Kirking, Elana Morris   +14 more
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A Trial of Lopinavir–Ritonavir in Adults Hospitalized with Severe Covid-19

New England Journal of Medicine, 2020
Background No therapeutics have yet been proven effective for the treatment of severe illness caused by SARS-CoV-2. Methods We conducted a randomized, controlled, open-label trial involving hospitalized adult patients with confirmed SARS-CoV-2 infection,
B. Cao, Ye-ming Wang, Danning Wen, Wen Liu, Jingli Wang, Guohui Fan, L. Ruan, Bin Song, Yanping Cai, M. Wei, Xing-wang Li, Jia’an Xia, Nanshan Chen, J. Xiang, Ting Yu, T. Bai, Xuelei Xie, Li Zhang, Caihong Li, Y. Yuan, Hua Chen, Huadong Li, Hanping Huang, Shengjin Tu, Fengyun Gong, Y. Liu, Yuan Wei, C. Dong, F. Zhou, Xiaoying Gu, Jiuyang Xu, Zhibo Liu, Yi Zhang, Hui Li, L. Shang, Ke Wang, Kunxia Li, Xia Zhou, Xuan Dong, Zhaohui Qu, S. Lu, Xujuan Hu, Shunan Ruan, S. Luo, Jing Wu, Lu Peng, Fang Cheng, L. Pan, Jun Zou, Chunming Jia, Juan Wang, Xia Liu, Shuzhen Wang, Xudong Wu, Qing Ge, Jingli He, Haiyan Zhan, Fang Qiu, Li Guo, Chaolin Huang, T. Jaki, F. Hayden, P. Horby, Dingyu Zhang, Chen Wang   +64 more
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COVID-19 case management strategies: what are the options for Africa?

Infectious Diseases of Poverty, 2021
The ongoing coronavirus disease 2019 (COVID-19) pandemic has put a strain on health systems globally. Although Africa is the least affected region to date, it has the weakest health systems and an exponential rise in cases as has been observed in other ...
Joy Luba Lomole Waya, David Ameh, Joseph Lou K. Mogga, Joseph F. Wamala, Olushayo Oluseun Olu   +4 more
doaj   +1 more source

OpenSAFELY: factors associated with COVID-19 death in 17 million patients

Nature, 2020
Coronavirus disease 2019 (COVID-19) has rapidly affected mortality worldwide1. There is unprecedented urgency to understand who is most at risk of severe outcomes, and this requires new approaches for the timely analysis of large datasets.
E. Williamson, A. Walker, K. Bhaskaran, S. Bacon, C. Bates, C. Morton, H. Curtis, A. Mehrkar, D. Evans, P. Inglesby, J. Cockburn, H. Mcdonald, B. Mackenna, L. Tomlinson, I. Douglas, C. Rentsch, R. Mathur, A. Wong, R. Grieve, D. Harrison, H. Forbes, A. Schultze, R. Croker, J. Parry, F. Hester, S. Harper, R. Perera, S. Evans, L. Smeeth, B. Goldacre   +29 more
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Moving from rhetoric to action: how Africa can use scientific evidence to halt the COVID-19 pandemic

Infectious Diseases of Poverty, 2020
The ongoing pandemic of the coronavirus disease 2019 has spread rapidly to all countries of the world. Africa is particularly predisposed to an escalation of the pandemic and its negative impact given its weak economy and health systems.
Olushayo Oluseun Olu, Joy Luba Lomole Waya, Sylvester Maleghemi, John Rumunu, David Ameh, Joseph Francis Wamala   +5 more
doaj   +1 more source

Using social and behavioural science to support COVID-19 pandemic response

Nature Human Behaviour, 2020
The COVID-19 pandemic represents a massive global health crisis. Because the crisis requires large-scale behaviour change and places significant psychological burdens on individuals, insights from the social and behavioural sciences can be used to help ...
J. V. Bavel, Katherine Baicker, Paulo S Boggio, V. Capraro, A. Cichocka, A. Cichocka, M. Cikara, M. Crockett, A. Crum, K. M. Douglas, James N. Druckman, J. Drury, Oeindrila Dube, N. Ellemers, E. Finkel, J. Fowler, M. Gelfand, Shihui Han, S. Haslam, J. Jetten, S. Kitayama, D. Mobbs, L. Napper, D. Packer, Gordon Pennycook, Ellen Peters, R. Petty, David G. Rand, S. Reicher, S. Schnall, A. Shariff, L. Skitka, S. Smith, C. Sunstein, Nassim Tabri, Joshua A. Tucker, S. Linden, P. Lange, Kim A. Weeden, Michael J. A. Wohl, Jamil Zaki, S. Zion, Robb Willer   +42 more
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Critical appraisal in rapid systematic reviews of COVID-19 studies: implementation of the Quality Criteria Checklist (QCC)

Systematic Reviews, 2023
In this letter, we briefly describe how we selected and implemented the quality criteria checklist (QCC) as a critical appraisal tool in rapid systematic reviews conducted to inform public health advice, guidance and policy during the COVID-19 pandemic ...
Daphne Duval, Nicola Pearce-Smith, Jennifer C. Palmer, Jason Kwasi Sarfo-Annin, Paul Rudd, Rachel Clark   +5 more
doaj   +1 more source