Results 241 to 250 of about 7,699,553 (352)

Health training – preparing an organism for coping with COVID-19 [PDF]

open access: gold, 2019
Piotr Gawda   +3 more
openalex   +1 more source

The NSP5, ORF6 and NSP13 of SARS‐CoV‐2 Cooperate to Modulate Inflammatory Cell Death Activation

open access: yesAdvanced Science, EarlyView.
ZBP1 is capable of initiating a large cell death complex to induce programmed cell death during SARS‐CoV‐2 infection. However, SARS‐CoV‐2 can inhibit the activation of ZBP1‐mediated cell death by targeting key components of this complex. This suppression of ZBP1‐mediated cell death may account for the increased mortality observed in patients co ...
Huan Wang   +16 more
wiley   +1 more source

Vaccination against COVID-19 and Outcomes in Patients with COVID-19 Infection and Stroke. [PDF]

open access: yesNPJ Vaccines
El Seblani N   +5 more
europepmc   +1 more source

Personalized Medication for Chronic Diseases Using Multimodal Data‐Driven Chain‐of‐Decisions

open access: yesAdvanced Science, EarlyView.
A MDD‐CoD is proposed for personalized chronic disease medication. The framework simulates clinical chain‐of‐decisions through three linked deep learning tasks, validated on multi‐center datasets (3 hospitals, 4 diseases), demonstrating enhanced generalization and interpretability in cross‐disease applications.
Xiaoli Chu   +10 more
wiley   +1 more source

Dyspnea is a Conundrum in the COVID-19 Era - A Case Report

open access: gold, 2017
Nithya Rajendran   +4 more
openalex   +1 more source

Targeting Neutrophil/Eosinophil Extracellular Traps by Aptamer‐Functionalized Nanosheets to Overcome Recalcitrant Inflammatory Disorders

open access: yesAdvanced Science, EarlyView.
In this study, C‐TAH, as multifunctional nanosheets, is developed with tannic acid and histone aptamer coverage. C‐TAH displays mild cytotoxicity, robust dsDNA and NETs/EETs binding efficiency, and potent antioxidant and antibacterial ability in vitro. C‐TAH treatment ameliorates dysregulated inflammation and restores hearing function in animal models,
Yongqiang Xiao   +13 more
wiley   +1 more source

RESP2: An Uncertainty Aware Multi‐Target Multi‐Property Optimization AI Pipeline for Antibody Discovery

open access: yesAdvanced Science, EarlyView.
RESP2, an enhanced antibody discovery pipeline for multi‐target and multi‐property optimization, identifies antibodies with optimized developability and broad affinity to multiple antigen variants. In silico evaluation shows RESP2 outperforms leading AI methods, achieving ≥85% success rates.
Jonathan Parkinson   +3 more
wiley   +1 more source

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