Results 71 to 80 of about 2,358,953 (205)

Age Moderates the Effect of Obesity on Mortality Risk in Critically Ill Patients With COVID-19: A Nationwide Observational Cohort Study [PDF]

, 2023
OBJECTIVES: A high body mass index (BMI) is associated with an unfavorable disease course in COVID-19, but not among those who require admission to the ICU. This has not been examined across different age groups.
Dutch COVID-19 Research Consortium
core  

Harnessing Nanohybridized Niclosamide for Precision Mpox Therapeutics

Advanced Healthcare Materials, EarlyView.
This study investigates the potential of nanohybridized niclosamide as a therapeutic agent for Mpox, focusing on enhanced bioavailability, improved antiviral efficacy, and controlled drug release achieved through nanoengineering. The research emphasizes significant advancements in formulation strategies, mechanistic insights, and therapeutic outcomes ...
N. Sanoj Rejinold, Geun‐woo Jin, Jin‐Ho Choy   +2 more
wiley   +1 more source

Smart Dust for Chemical Mapping

Advanced Materials, EarlyView.
This review article explores the advancement of smart dust networks for high‐resolution spatial and temporal chemical mapping. Comprising miniature, wireless sensors, and communication devices, smart dust autonomously collects, processes, and transmits data via swarm‐based communication.
Indrajit Mondal, Hossam Haick
wiley   +1 more source

Formulation and Characterization of Novel Ionizable and Cationic Lipid Nanoparticles for the Delivery of Splice‐Switching Oligonucleotides

Advanced Materials, EarlyView.
Lipid nanoparticles (LNPs) of unconventional composition and defined structures are investigated as small oligonucleotide carriers. A composition is identified that outperforms Onpattro in cargo delivery to HeLa cells. The structure of these LNPs resembles a micellar cubic phase not commonly associated with high‐performing LNPs.
Miina Ojansivu, Hanna M. G. Barriga, Margaret N. Holme, Stefanie Morf, James J. Doutch, Samir EL Andaloussi, Tomas Kjellman, Markus Johnsson, Justas Barauskas, Molly M. Stevens   +9 more
wiley   +1 more source

Inquérito Serológico Nacional COVID-19 (3ª fase): relatório de apresentação dos resultados [PDF]

, 2021
Instituto Nacional de Saúde Doutor Ricardo Jorge: Ana Paula Rodrigues (coordenação).Grupo ISN COVID-19: lista completa da equipa, laboratórios, unidades de saúde e instituições parceiras consta nas páginas 3-6 do relatório.Versão 2 atualizada em 28-7 ...
Grupo ISN COVID-19
core   +1 more source

Transforming Healthcare: Intelligent Wearable Sensors Empowered by Smart Materials and Artificial Intelligence

Advanced Materials, EarlyView.
Wearable sensors, empowered by AI and smart materials, revolutionize healthcare by enabling intelligent disease diagnosis, personalized therapy, and seamless health monitoring without disrupting daily life. This review explores cutting‐edge advancements in smart materials and AI‐driven technologies that empower wearable sensors for diagnostics and ...
Shuwen Chen, Shicheng Fan, Zheng Qiao, Zixiong Wu, Baobao Lin, Zhijie Li, Michael A. Riegler, Matthew Yu Heng Wong, Arve Opheim, Olga Korostynska, Kaare Magne Nielsen, Thomas Glott, Anne Catrine T. Martinsen, Vibeke H. Telle‐Hansen, Chwee Teck Lim   +14 more
wiley   +1 more source

A Sustainable Route From Quartz to Bifunctional Material with Adsorbed Lanthanides for Enhanced Fluorescent Activation in Doxycycline Sensing

Advanced Materials Interfaces, EarlyView.
The aim of this study is to develop a sensor material based on natural quartz combined with La(III) and Ce(III), both detected in Ni‐MH batteries, as well as Eu(III), for reliable qualitative and quantitative analysis of doxycycline over a broad concentration range.
Olha Semeshko, Maksym Fizer, Valeriia Sliesarenko, Jaroslav Briancin, Oleksandr Bondarchuk, Aleksandra Lobnik, Inna Melnyk   +6 more
wiley   +1 more source

Fast Prototyping and Ex Vivo Evaluation of Dissolvable Millineedle Patches Made by Solvent Casting from CO2 Laser Ablated Elastomer Molds

Advanced Materials Interfaces, EarlyView.
CO2 laser ablation, a fast, inexpensive, and reproducible method, is used to create flexible elastomer molds with millimeter‐long cavities for the fabrication of dissolvable polymer needles. Made from PVP, these milli‐needles achieve ≈560 µm penetration into porcine skin, demonstrating their potential for effective transdermal drug delivery.
Matteo Tollemeto, Lasse Højlund Eklund Thamdrup, Veni Mahalingam, Gavrielle R. Untracht, Tania Patiño Padial, Peter Eskil Andersen, Jan van Hest, Anja Boisen   +7 more
wiley   +1 more source

Automated identification of patient subgroups: A case-study on mortality of COVID-19 patients admitted to the ICU [PDF]

, 2023
BACKGROUND: - Subgroup discovery (SGD) is the automated splitting of the data into complex subgroups. Various SGD methods have been applied to the medical domain, but none have been extensively evaluated.
Dutch COVID-19 ICU Research Consortium
core  

Evaporation‐Enhanced Redox Cycling for Rapid Detection of Attomolar SARS‐CoV‐2 Virions Using Nanolithography‐Free Electrochemical Devices

Advanced Materials Technologies, EarlyView.
This study presents microfabricated electrochemical sensors for detecting ultralow viral particles counts through evaporation‐enhanced redox cycling (E2RC). To achieve sub‐micrometer gap in interdigitated microelectrodes, a scalable, nanolithography‐free fabrication method is developed.
Pouya Soltan Khamsi, Vinay Kammarchedu, Aida Ebrahimi   +2 more
wiley   +1 more source