Results 81 to 90 of about 5,127,009 (325)
Jornal de Pediatria, 2021 This narrative, non-systematic review provides an update on the genetic aspects of the SARS-CoV-2 virus and its interactions with the human genome within the context of COVID-19. Although the main focus is on the etiology of this new disease, the genetics of SARS-CoV-2 impacts prevention, diagnosis, prognosis, and the development of therapies.A ...
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Cardiovascular Implications of Fatal Outcomes of Patients With Coronavirus Disease 2019 (COVID-19)
JAMA cardiology, 2020 This case series study evaluates the association of underlying cardiovascular disease and myocardial injury on fatal outcomes in patients with coronavirus disease 2019 (COVID-19).
T. Guo +9 more
semanticscholar +1 more source
FEBS Open Bio, EarlyView.Cleavable N‐terminal Thioredoxin fusion enabled soluble expression and purification of otherwise insoluble SARS‐CoV‐2 Nucleocapsid (N) protein. A four‐step purification strategy yielded highly homogeneous, RNA‐free N protein. Binding assays showed high RNA affinity (Kd ~ 28 nm). The study will facilitate high‐resolution structural studies of N protein,
Shweta Singh, Gagan D. Gupta
wiley +1 more source
, 2020 Discussion of scholar papers published on Ivermectin and of some news that we can find about its use for Covid-19. A list of clinical trials is also given. The discussion was made in a series of versions from 14 June to 27 July 2020. For what concerns scholar papers, we report among them a preprint posted on 10 June in MedRχiv, which concludes that ...
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Nature Reviews Physics, 2020 As the COVID-19 pandemic continues, mathematical epidemiologists share their views on what models reveal about how the disease has spread, the current state of play and what work still needs to be done.
Bernardo Gutierrez +15 more
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A 2-month field cohort study of SARS-CoV-2 in saliva of BNT162b2 vaccinated nursing home workers
Communications Medicine, 2022 Saegerman et al. perform saliva SARS-CoV-2 testing in a cohort of nursing home workers in Belgium who are either unvaccinated or have received one or two doses of the BNT162b2 mRNA vaccine.
Claude Saegerman +18 more
doaj +1 more source
Frontiers in Public Health, 2023 The rising demand for medicinal oxygen due to the COVID-19 pandemic exacerbated an underlying chronic shortage of the commodity in Africa. This situation is particularly dire in protracted crises where insecurity, dysfunctional health facilities, poor ...
Olushayo Oluseun Olu +6 more
doaj +1 more source
Association of Cardiac Injury With Mortality in Hospitalized Patients With COVID-19 in Wuhan, China.
JAMA cardiology, 2020 Importance Coronavirus disease 2019 (COVID-19) has resulted in considerable morbidity and mortality worldwide since December 2019. However, information on cardiac injury in patients affected by COVID-19 is limited.
Shao-bo Shi +12 more
semanticscholar +1 more source
FEBS Open Bio, EarlyView.Papain‐like protease from SARS‐CoV‐2 plays an important role in the cleavage of the viral polyproteins and in the suppression of the host's immune response. Here, we present the results of an NMR screening study. We identified 86 binding compounds, of which five candidates were chosen for in‐depth analysis.
Dennis J. Pyper +5 more
wiley +1 more source
Dysregulation of immune response in patients with COVID-19 in Wuhan, China
Clinical Infectious Diseases, 2020 Background In December 2019, coronavirus disease 2019 (COVID-19) emerged in Wuhan and rapidly spread throughout China. Methods Demographic and clinical data of all confirmed cases with COVID-19 on admission at Tongji Hospital from January 10 to February ...
C. Qin +10 more
semanticscholar +1 more source