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ADME and Pharmacokinetic Properties of Remdesivir: Its Drug Interaction Potential [PDF]
On 11 March 2020, the World Health Organization (WHO) classified the Coronavirus Disease 2019 (COVID-19) as a global pandemic, which tested healthcare systems, administrations, and treatment ingenuity across the world.
Subrata Deb+3 more
doaj +3 more sources
Repurposed pharmacological agents for the potential treatment of COVID-19: a literature review [PDF]
Background The COVID-19 pandemic has affected the world extraordinarily. This disease has a potential to cause a significantly severe course of disease leading to respiratory complications, multiple organ failure and possibly death.
Alina Kröker, Madara Tirzīte
doaj +2 more sources
Current Status of Baricitinib as a Repurposed Therapy for COVID-19 [PDF]
The emergence of the COVID-19 pandemic has mandated the instant (re)search for potential drug candidates. In response to the unprecedented situation, it was recognized early that repurposing of available drugs in the market could timely save lives, by ...
Maha Saber-Ayad+6 more
doaj +3 more sources
Analysis of the efficacy of Chinese medicine in the treatment of covid-19 and the study of medication pattern [PDF]
In order to explore the efficacy and medication pattern of Chinese medicine in the treatment of COVID-19, we conducted statistics on the medication use of Chinese medicine based on some clinical data of novel coronavirus pneumonia (COVID-19) and related ...
Cong Xiaoqing, Ren Xiaoqiang
doaj +1 more source
Drug Repurposing for COVID-19 Treatment by Integrating Network Pharmacology and Transcriptomics
Since coronavirus disease 2019 (COVID-19) is a serious new worldwide public health crisis with significant morbidity and mortality, effective therapeutic treatments are urgently needed.
Dan-Yang Liu+7 more
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Purpose: Current understanding of COVID-19 disease progression suggests a major role for the “cytokine storm” as an important contributor to COVID-19 mortality.
Yewon Park+4 more
doaj +1 more source
Pharmacogenetics Approach for the Improvement of COVID-19 Treatment
The treatment of coronavirus disease 2019 (COVID-19) has been a challenge. The efficacy of several drugs has been evaluated and variability in drug response has been observed.
Ingrid Fricke-Galindo+1 more
doaj +1 more source
Drug‐drug interactions with candidate medications used for COVID‐19 treatment: An overview
Drug‐drug interaction (DDI) is a common clinical problem that has occurred as a result of the concomitant use of multiple drugs. DDI may occur in patients under treatment with medications used for coronavirus disease 2019 (COVID‐19; i.e., chloroquine ...
Haleh Rezaee+5 more
doaj +1 more source
Background The efficacy of antiviral drugs that neutralize antibody drugs and fight against SARS-COV-2 is reported to be attenuated by genetic mutations of the virus in vitro.
Haruka Shimazu+9 more
doaj +1 more source
Evaluation of potential drug-drug interactions and polypharmacy in hospitalized COVID-19 patients [PDF]
Background: Drugs that are used in COVID-19 infection, may interact with each other, as well as with the drugs for comorbidities, used concomitantly with COVID-19 treatment.
Erarslan, Sertaş+3 more
core +2 more sources