Results 121 to 130 of about 749,586 (230)

Accelerating Primary Screening of USP8 Inhibitors from Drug Repurposing Databases with Tree‐Based Machine Learning

Advanced Intelligent Discovery, EarlyView.
This study introduces a tree‐based machine learning approach to accelerate USP8 inhibitor discovery. The best‐performing model identified 100 high‐confidence repurposable compounds, half already approved or in clinical trials, and uncovered novel scaffolds not previously studied. These findings offer a solid foundation for rapid experimental follow‐up,
Yik Kwong Ng, Sharon Ai Er Lam, Wei Chun Lim, Hannah Hui Min Toh, Shi Jun Ang   +4 more
wiley   +1 more source

Impact of the COVID-19 pandemic on infant neurodevelopmental outcomes. [PDF]

BMJ Paediatr Open
Kyono Y, Nishiyama M, Yamaguchi H, Kawamura A, Oikawa S, Tokumoto S, Imai T, Murakami S, Nozu K, Mishina H, Nagase H.   +10 more
europepmc   +1 more source

Machine Learning‐Augmented Loop‐Mediated Isothermal Amplification‐Enabled Point‐of‐Care for Mpox‐Specific Detection

Advanced Intelligent Systems, EarlyView.
A low‐cost, portable point‐of‐care platform for rapid Mpox detection using loop‐mediated isothermal amplification is reported. The device integrates fluorescence readout and mobile monitoring. A machine‐learning model analyzes temperature data and correlates thermal changes with DNA concentration, enabling sensitive and reliable molecular diagnosis in ...
Nazente Atceken, Ahmed Choukri Abdullah, Olgac Ozarslan, Ziya Yıldız, Savas Tasoglu   +4 more
wiley   +1 more source

From Covid 19 pandemic to germline genome editing

Humana.Mente: Journal of Philosophical Studies
This text explores the intricate relationship between personal autonomy and public health objectives, particularly accentuated during the recent pandemic. Emphasising the challenge of balancing individual autonomy with broader public health imperatives,
Maurizio Balistreri
doaj  

Impact of the COVID-19 pandemic on the health situation of the Brazilian population. [PDF]

Braz J Infect Dis
Szwarcwald CL, de Almeida WDS, de Souza Junior PRB, de Castilho EA, Damacena GN, Gomes CS, Malta DC.   +6 more
europepmc   +1 more source

Lost in aggregation? On the importance of local food price data for food poverty estimates

American Journal of Agricultural Economics, EarlyView.
Abstract This paper explores within‐country variations in food price dynamics and food poverty estimates by employing local market price data and national consumer price index (CPI) data. Our results show that national CPI data may be useful for approximating national trends but they fail to detect and identify spatial variations in local trends, which
Stephan Dietrich, Valerio Giuffrida, Bruno Martorano, Georg Schmerzeck, Marco Tiberti   +4 more
wiley   +1 more source

Safe cancer surgery during the COVID- 19 pandemic

Asian Journal of Surgery, 2020
Elif Colak, Mustafa Safa Uyanik
doaj   +1 more source

Tuberculosis before and during COVID-19 Pandemic, United States, 2010-2023. [PDF]

Emerg Infect Dis
Feng PI, Phares CR, Pratt R, Self JL.
europepmc   +1 more source

Mental health service use among Filipino American and Korean American young adults during the COVID‐19 pandemic

American Journal of Community Psychology, EarlyView.
Abstract Despite the heightened mental health challenges amid rising Anti‐Asian sentiment, Asian Americans have significantly underutilized mental health services, a trend that persisted even before the COVID‐19 pandemic. Although considerable efforts have been made to understand how various factors are related to mental health service use in this ...
Michael Park, Eunseok Jeong, Nari Yoo, Yoonsun Choi, Leopoldo J. Cabassa, Miwa Yasui, David Takeuchi   +6 more
wiley   +1 more source

Vaping during the COVID‐19 pandemic: NOT GOOD!!

Laryngoscope Investigative Otolaryngology, 2020
Willard C. Harrill
doaj   +1 more source