Results 141 to 150 of about 3,495,692 (358)
Impact of COVID-19 pandemic on mental health in the general population: A systematic review
Journal of Affective Disorders, 2020 Jiaqi Xiong, Orly Lipsitz, F. Nasri, L. Lui, H. Gill, Lee Phan, D. Chen-Li, M. Iacobucci, R. Ho, Amna Majeed, R. McIntyre +10 moresemanticscholar +1 more sourceQuality of life in medical students during the COVID-19 pandemic
, 2021 Shastri Motilal, Jordan E. Taylor, Kaveer Sookram, Shivana Sooknanan, Shivana Sooknanan, Joanna Sookoo, Shekeela Stroude, Chelsea Sudama, Tanya Tatiparthi, Hannah M. Thompson +9 moreopenalex +1 more sourceA Rationally Engineered Spleen‐Tropic One‐Component Lipid‐mRNA Complex (OncoLRC) for Cancer Vaccines
Advanced Science, EarlyView.OncoLRC, a one‐component lipid‐mRNA complex, enables efficient spleen‐targeted delivery at an exceptionally low lipid‐to‐mRNA mass ratio (1.5:1), robustly activates immune responses, inhibits tumor growth, and synergizes with checkpoint blockade, presenting a next‐generation platform for mRNA vaccines.Qimeng Yin, Chenchen Zhang, Jiahao Li, Kun Huang, Min Qiu +4 morewiley +1 more sourceHost‐Directed Antiviral Activity of SB2960 Through Selective Induction and Remodeling of Stress Granules
Advanced Science, EarlyView.Amid the ongoing threat of emerging viral pathogens, host‐directed antivirals offer a strategy to overcome viral mutation and drug resistance. SB2960, a small‐molecule inducer of stress granules (SGs), exhibits potent broad‐spectrum antiviral activity with minimal cytotoxicity.Wan Gi Byun, Sumin Son, JinAh Lee, Minha Lee, Meehyun Ko, Songrui Zhao, Ju Hee Kim, Kannan Vaithegi, Ji Hoon Kwon, Jung Ho Lee, Sangeun Jeon, Dawon Yi, Peng Zou, Seungtaek Kim, Seung Bum Park +14 morewiley +1 more sourceMultidisciplinary research priorities for the COVID-19 pandemic: a call for action for mental health science
Lancet psychiatry, 2020 Emily A. Holmes, Emily A. Holmes, R. O’Connor, V. Perry, I. Tracey, S. Wessely, L. Arseneault, C. Ballard, H. Christensen, R. C. Silver, I. Everall, T. Ford, A. John, T. Kabir, Kate King, I. Madan, S. Michie, Andrew K. Przybylski, R. Shafran, A. Sweeney, C. Worthman, L. Yardley, K. Cowan, C. Cope, M. Hotopf, E. Bullmore +25 moresemanticscholar +1 more sourceEstimating excess mortality due to the COVID-19 pandemic: a systematic analysis of COVID-19-related mortality, 2020–21
The Lancet, 2022 Haidong Katherine R Spencer A Stefanie Haley Peng Aleksand Wang Paulson Pease Watson Comfort Zheng Aravkin Bi, Haidong Wang, Katherine R Paulson, Spencer A Pease, S. Watson, H. Comfort, Peng Zheng, A. Aravkin, C. Bisignano, Ryan Barber, Tahiya Alam, J. Fuller, Erin A May, Darwin P. Jones, Meghan E Frisch, C. Abbafati, C. Adolph, A. Allorant, Joanne O Amlag, Bree L Bang-Jensen, Gregory J. Bertolacci, Sabina S Bloom, A. Carter, Emma Castro, Suman Chakrabarti, Jhilik Chattopadhyay, Rebecca M. Cogen, J. Collins, Kimberly Cooperrider, X. Dai, W. J. Dangel, Farah Daoud, Carolyn Dapper, A. Deen, B. Duncan, Megan Erickson, Samuel B. Ewald, Tatiana Fedosseeva, A. Ferrari, J. Frostad, N. Fullman, J. Gallagher, A. Gamkrelidze, Gaorui Guo, Jiawei He, Monika Helak, N. Henry, E. Hulland, Bethany M. Huntley, M. Kereselidze, Alice Lazzar-Atwood, K. E. LeGrand, Akiaja Lindstrom, Emily Linebarger, P. Lotufo, R. Lozano, Beatrice Magistro, D. Malta, J. Månsson, A. M. Mantilla Herrera, F. Marinho, A. Mirkuzie, A. Misganaw, L. Monasta, Paulami Naik, Shuhei Nomura, Edward G O'Brien, J. K. O'Halloran, Latera Tesfaye Olana, Samuel M. Ostroff, Louise Penberthy, Robert C Reiner Jr., Grace Reinke, A. L. Ribeiro, D. Santomauro, M.I. Schmidt, David H. Shaw, Brittney S. Sheena, A. Sholokhov, N. Skhvitaridze, Reed J. D. Sorensen, E. Spurlock, Ruri Syailendrawati, R. Topor-Madry, C. Troeger, R. Walcott, Ally Walker, C. Wiysonge, N. Worku, B. Zigler, D. Pigott, M. Naghavi, A. Mokdad, Stephen S. Lim, Simon Iain Hay, E. Gakidou, C. Murray +96 moresemanticscholar +1 more sourceGenome‐Wide Codon Reprogramming Enables a Multifactorially Attenuated Influenza Vaccine with Broad Cross‐Protection
Advanced Science, EarlyView.Genome‐wide codon reprogramming of influenza A virus introduces 1956 synonymous mutations across five segments and elevates CpG content, causing defective NA packaging, loss of NS1 accumulation, and enhanced ZAP‐mediated antiviral responses without affecting RNA or protein synthesis. These mechanisms result in profound attenuation and potent homologous Yang Wang, Tianxin Ma, Yujiao He, Qinming Li, Kailin Mai, Minying Mo, Chenyang Cao, Jiahui Li, Pei Feng, Jiaojiao Peng, Jing Sun, Weiqi Pan, Zifeng Yang, Ling Chen +13 morewiley +1 more source