Results 151 to 160 of about 2,725,203 (258)

Cardiovascular and mortality risks following COVID-19-related versus non-COVID-19-related chronic obstructive pulmonary disease exacerbations. [PDF]

Ann Am Thorac Soc
Kirui BK, Li H, Wallström O, Vanfleteren LEGW, Santosa A, Bonander C, Stridsman C, Börjesson M, Nyberg F.   +8 more
europepmc   +1 more source

Advances in Aptamer Drug Delivery Systems for Treatment of Glioblastoma

Advanced Science, EarlyView.
Aptamers have remarkable recognition capacity which is suitable for assisting drug delivery for GB. This review demonstrates that aptamers have great potential as targeted therapeutic carriers, conjugated to various therapeutic carriers, using a range of conjugation strategies and chemistries.
Alexandra R. Paul, Alexandra Moreno Mitchell, Dean O'Neil, Yutong Luo, Khuloud T. Al‐Jamal   +4 more
wiley   +1 more source

Thalidomide combined with low‐dose short‐term glucocorticoid in the treatment of critical Coronavirus Disease 2019

Clinical and Translational Medicine, 2020
Chengshui Chen, Feng Qi, Keqing Shi, Yuping Li, Ji Li, Yongping Chen, Jingye Pan, Tieli Zhou, Xiangyang Lin, Jinsan Zhang, Yongde Luo, Xiaokun Li, Jinglin Xia   +12 more
doaj   +1 more source

Detaching Photosensitive Nanoparticles from Cells Prevents Them from Remaining in Cells after Photoporation

Advanced Science, EarlyView.
Phenylboronic acid‐functionalized gold nanoparticles reversibly attach to cell‐surface glycans, enhancing photoporation‐mediated intracellular delivery. After irradiation, ATP competitively disrupts the boronic ester interactions and removes cell‐associated nanoparticles, markedly reducing residual gold.
Tao Lu, Mina Nikolić, Baihao Huang, Deep Punj, Herlinde De Keersmaecker, Thibaut Van Acker, Wenjia Xie, Florian Vanlauwe, Phillip Blondeel, Liesl De Graeve, Félix Sauvage, Ranhua Xiong, Chaobo Huang, Frank Vanhaecke, Kevin Braeckmans, Stefaan C. De Smedt   +15 more
wiley   +1 more source

Transport–Reaction–Signal Coupling in Lateral Flow Assays for Next‐Generation Point‐of‐Care Diagnostics

Advanced Science, EarlyView.
Lateral flow assays are evolving into interdisciplinary, system‐level sensing platforms. Recent innovations are deconstructed through coupled phases of mass transfer, reaction, and signal transduction, revealing interdependence across porous materials, interfacial chemistry, nanolabels, readout devices, and data‐enabled analysis.
Yan Pan, Yuewei Li, Chao Mi, Zhengwen Yang, Lana McClements, Steven J. Langford, Jiayan Liao   +6 more
wiley   +1 more source

Benefit and risk assessment for COVID-19 vaccines

COVID-09-Wallace-508 ...

core  

Immune Checkpoint Inhibitor as a Fifth Component of Lipid Nanoparticles Enables Lymph Node‐Targeting and Augments mRNA Vaccine Efficacy

Advanced Science, EarlyView.
Here, a PDL1 inhibitor is employed as a fifth component to modify lipid nanoparticles (LNPs). PDL1 inhibitor‐loaded LNPs show enhanced lymph node targeting, resulting in greater lymph node expansion, immune cell infiltration, and improved mRNA vaccine efficacy. This fifth component LNP could be a novel platform for mRNA vaccines.
Minki Ha, Jaehyun Kim, Seyoung Kim, Gonna Somu Naidu, Sungchan Cho, Seok‐Beom Yong   +5 more
wiley   +1 more source

National Forum on COVID-19 Vaccine : practitioners

Practitioners have been and continue to be on the front lines in the fight against COVID-19. Now that COVID-19 vaccines are available, work must continue to deliver safe, effective, and equitable vaccination to people in communities across the country ...

core  

Booster dose of COVID-19 vaccine and its effectiveness against post COVID-19 condition in individuals with pre-existing immunity: a sequential propensity score-matched cohort study. [PDF]

EClinicalMedicine
Morris L, Bülow E, Li H, Xu Y, Gisslén M, Nyberg F, Bygdell M.   +6 more
europepmc   +1 more source

Public health challenges posed by delays in obtaining COVID-19 clearance for long-distance truckers across East Africa

Global Epidemiology, 2020
John Gachohi, Jane Aduda, Reuben Thuo, Joseph Mung'atu, Fred Wamunyokoli, Thomas Ngigi, Henry Athiany, Gideon Kikuvi, Susan Mambo, Wairimu Gichaiya, Joseph Matheri, Patrick Mburugu, Justus Simba, Carol Otiwa, Charles Muriuki, Joshua Mwaura, May Yariwo, Beatrice Kariuki, Joseph Machua, Catherine Mwangi, Patrick Amoth, Rashid Aman, Onesmus Kamau, Kennedy Muthoka, Jacob Otieno, Pascal Mwele, Rose Nzioka, Simon Karanja   +27 more
doaj   +1 more source