Results 181 to 190 of about 6,183,390 (300)

OAF Blocks SIAH1‐Mediated Degradation of SCPX, a Therapeutic Strategy for MASLD

Advanced Science, EarlyView.
This study shows OAF directly binds to SCPX and inhibits its interaction with the E3 ligase SIAH1, thereby protecting SCPX from ubiquitin‐dependent degradation and stabilizing its levels. This OAF‐SCPX axis represents a novel pathway in lipid homeostasis, highlighting OAF as a promising therapeutic candidate for MASLD.
Zongxi Li, Jingyue Song, Kaili Ma, Shunan Tang, Shuqian Wang, Wenya Ji, Chen Lu, Ting Zhang, Huaping Zheng, Xiaowei Zheng, Shanshan Lai, Cheng Deng   +11 more
wiley   +1 more source

Niche‐Mediated Neural Priming Enables Robust and Scalable Generation of Human Choroid Plexus Organoids

Advanced Science, EarlyView.
Compared to E8, mTeSR1 culture downregulated WNT and TGF‑β signaling, and upregulated neural differentiation pathways, enhancing neural priming. Under skin organoid induction conditions, mTeSR1‑cultured hESCs generated organoids with significantly higher neuroepithelial differentiation.
Zhongliang Chen, Liangxia Jiang, Xianbin Wang, Lili Zhong, Rongcan Luo, Min Su, Liangzhao Chu, Peng Luo   +7 more
wiley   +1 more source

Tuberculosis (TB) service utilisation pre and peri-COVID-19 restrictions in Johannesburg, Gauteng. [PDF]

S Afr Fam Pract (2004)
Maluleke VH, Smith L.
europepmc   +1 more source

COVID-19 science update ; Edition 2020-23-10

From the Office of the Chief Medical Officer, CDC COVID-19 Response, and the CDC Library, Atlanta GA. Intended for use by public health professionals responding to the COVID-19 pandemic.2020_10_23_Science-Update_Final_Public.pdfThe True Burden of COVID ...

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Ultrastable Self‐Cross‐linkable Electro‐Optic Materials Based on a Bisanthracene Scaffold

Advanced Electronic Materials, EarlyView.
A novel bisanthracene‐based self‐cross‐linkable electro‐optic chromophore (TD2) is developed. TD2 exhibits a high r33 of 141 pm/V and a cross‐linked Tg up to 195 °C, retaining 99.75% of its initial EO response after 500 h at 85 °C, showing record‐high thermal stability for single‐molecule self‐cross‐linking EO materials.
Xingtao Wang, Zhifan Liu, Qinghua Yang, Jiayan Xu, Lin Li, Fenggang Liu, Shengyu Cong   +6 more
wiley   +1 more source

Transcriptomics of severe COVID-19. [PDF]

Vavilovskii Zhurnal Genet Selektsii
Gusarova AA, Trifonova EA, Babovskaya AA, Gavrilenko MM, Stepanov VA.   +4 more
europepmc   +1 more source

COVID-19 science update ; Edition 2021-07-16 (98)

From the Office of the Chief Medical Officer, CDC COVID-19 Response, and the CDC Library, Atlanta GA. Intended for use by public health professionals responding to the COVID-19 pandemic.Disclaimer: The purpose of the CDC COVID-19 Science Update is to ...

core  

Safety of Sodium‐Ion Batteries: Evaluation and Perspective from Component Materials to Cells, Modules, and Packs

Advanced Energy Materials, EarlyView.
This review provides a bottom‐up evaluation of sodium‐ion battery safety, linking material degradation mechanisms, cell engineering parameters, and module/pack assembly. It emphasizes that understanding intrinsic material stability and establishing coordinated engineering control across hierarchical levels are vital for preventing degradation coupling ...
Won‐Gwang Lim, Seoa Kim, Erik A. Wu, Darren H. S. Tan, Shawn Peng, Xiaolin Li   +5 more
wiley   +1 more source

Characterization of Post COVID‑19 pneumo‑hematocele in the largest COVID-19 center in Mexico City. [PDF]

J Cardiothorac Surg
Castrillo-Hernández GE, Pimienta-Ibarra AS, Barrientos-Morales EG, Solares-Espinoza AG, Dávila-Conn V, Hérnandez-Cárdenas CM, Castorena-Maldonado AR, Bolaños FV, Juárez-Armenta AL.   +8 more
europepmc   +1 more source

COVID-19 science update ; Edition 2020-09-18

From the Office of the Chief Medical Officer, CDC COVID-19 Response, and the CDC Library, Atlanta GA. Intended for use by public health professionals responding to the COVID-19 pandemic.Disclaimer: The purpose of the CDC COVID-19 Science Update is to ...

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