Results 111 to 120 of about 3,057,200 (307)

Metabolic and Fluid Biomarkers Support Microglia Activation in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Amyotrophic lateral sclerosis is an incurable neurodegenerative disease involving motor neuron degeneration and metabolic and immune dysfunction. We combined clinical data, cerebrospinal fluid biomarkers and fluorodeoxyglucose positron emission tomography with magnetic resonance imaging to investigate the role of reactive microglia in disease ...
Matteo Zanovello, Francesca Serani, Alen Bebeti, Federica Paredi, Giulia Quadrio, Andrea Fortuna, Giacomo Maria Minicuci, Elena Pegoraro, Annachiara Cagnin, Diego Cecchin, Gianni Sorarù   +10 more
wiley   +1 more source

Diffuse MRI Edema Predicts Relapse in Cerebral Amyloid Angiopathy–Related Inflammation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To identify MRI predictors of relapse and quantify relapse and mortality risk in cerebral amyloid angiopathy–related inflammation (CAA‐RI). A secondary objective was to assess the association between mycophenolate mofetil use and relapse risk. Methods We performed a retrospective cohort study of 36 patients with CAA‐RI treated at the
G. Abbas Kharal, Gowtham Yerneni, Kim J. Griffin, Nicolas Thompson, Ken Uchino, Irene Katzan, Dolora Wisco, Abeer Farrag, Jayashree Sundarajan, Andrew Russman, M. Shazam Hussain   +10 more
wiley   +1 more source

Cox-adjusted analysis regression model on one-year mortality in patients with prolonged MV with or without tracheostomy.

, 2019
Cox-adjusted analysis regression model on one-year mortality in patients with prolonged MV with or without tracheostomy.
Alexandre Mebazaa (58728), Samir Jaber (131956), Charles Damoisel (744993), Anaïs Caillard (6704759), Sebastian Voicu (6821561), Benjamin Chousterman (4873984), Haikel Oueslati (6116495), Etienne Gayat (159635), Fanny Feuillet (3471473), Antoine Roquilly (240368), Raphaël Cinotti (7456343), Catherine Paugam-Burtz (3581843)   +11 more
core   +1 more source

Clinical Impact of MGMT Promoter Methylation in IDH‐Mutant Gliomas: Influence of Threshold Selection and Clinical Confounding

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background The clinical relevance of MGMT promoter methylation in IDH‐mutant gliomas remains controversial in the era of molecular classification. We aimed to systematically evaluate its clinical relevance by integrating quantitative assessment, cutoff exploration, and adjustment for clinical confounding.
Haihui Jiang, Linxi Cao, Xiaodong Chen, Siqi Tong, Qinghui Zhu, Jun Yang, Song Lin, Yong Cui   +7 more
wiley   +1 more source

An individualized prognostic nomogram integrating clinical and pathological features in pediatric IgA vasculitis nephritis

Frontiers in Medicine
ObjectiveTo develop and validate an individualized prognostic nomogram integrating clinical and pathological features for estimating the risk of renal function decline in children with IgA vasculitis nephritis (IgAVN).MethodsIn this single-center ...
Yueheng Gan, Li Xiao, Shaojun Li, Anshuo Wang, Sijie Yu, Xuejun Yang, Mo Wang, Qiu Li, Han Chan, Haiping Yang   +9 more
doaj   +1 more source

Association of Serum Nonesterified Fatty Acids with Cardiovascular Event in Patients with Chronic Kidney Disease

International Journal of General Medicine, 2021
Chentang Wu,1 Xueyun Chen2 1Department of Cardiovascular Medicine, Mindong Hospital of Fujian Medical University, Fuan, Fujian, 355000, People’s Republic of China; 2Department of Endocrinology, Mindong Hospital of Fujian Medical University, Fuan ...
Wu C, Chen X
doaj  

microRNA‐7‐5p and α‐Synuclein SAA Predict Parkinson's Disease Phenoconversion

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Corroborate blood neuron‐derived extracellular vesicle (NDEV) alpha‐synuclein (αSyn), the CSF αSyn seed amplification assay (αSyn‐SAA), and blood microRNA‐7‐5p (miR‐7‐5p) as markers for Parkinson's disease (PD) phenoconversion and determine if combining these markers would help select subjects who would be more likely to phenoconvert.
Shayan Zadegan, Praveen Velammal, Kanmani Muthiah, Madhu Jatty, Christopher Adams   +4 more
wiley   +1 more source

Analysis of risk factors and prediction of prognosis in patients with primary liver cancer undergoing transarterial chemoembolization

Frontiers in Oncology
BackgroundTransarterial chemoembolization (TACE) is a key locoregional therapy for unresectable primary liver cancer, yet post-TACE survival remains heterogeneous. We evaluated prognostic determinants and developed a prediction model for overall survival.
Xu-Long Lu, Li-Min Yin
doaj   +1 more source

Impact of Nosocomial Infection on in-Hospital Mortality Rate in Adult Patients Under Venoarterial Extracorporeal Membrane Oxygenation After Cardiac Surgery

Infection and Drug Resistance, 2023
Xiyuan Li,1,2 Xiaomeng Wang,1 Liangshan Wang,1 Chenglong Li,1 Xing Hao,1 Zhongtao Du,1 Haixiu Xie,1 Feng Yang,1 Hong Wang,1 Xiaotong Hou1 1Center for Cardiac Intensive Care, Beijing Institute of Heart, Lung, and Blood Vessel Diseases, Beijing Anzhen ...
Li X, Wang X, Wang L, Li C, Hao X, Du Z, Xie H, Yang F, Wang H, Hou X   +9 more
doaj  

A Simple Test for the Absence of Covariate Dependence in Hazard Regression Models [PDF]

, 2004
This paper extends commonly used tests for equality of hazard rates in a two-sample or k-sample setup to a situation where the covariate under study is continuous.
Bhattacharjee, Arnab, Bhattacharjee, A., Bhattacharjee, A.; id_orcid, Bhattacharjee, Arnab; id_orcid   +3 more
core