Results 11 to 20 of about 13,876 (172)

<i>Coxiella burnetii</i> Infection Among Blood Donors From Baden-Wuerttemberg Province and Hesse Province, Germany: A Multicentre Cross-Sectional Serological Study. [PDF]

Public Health Chall
This study analyzes the seroprevalence of Coxiella burnetii in a German non‐risk population using a stratified sampling approach across two federal states (n = 8400 potential samples). Screening of over 5000 blood donors reveals an overall seroprevalence of 2.96%.
Dangel L, Hummel D, Kempf VAJ, Faber M, Hourfar K, Stefan B, Eichner M, Fischer SF.   +7 more
europepmc   +2 more sources

Coxiella

, 2023
Published as part of Su, Si, Hong, Mei, Cui, Meng-Yu, Gui, Zheng, Ma, Shi-Fa, Wu, Lin, Xing, Li-Li, Mu, Lan, Yu, Jing-Feng, Fu, Shao-Yin, Gao, Rui-Juan & Qi, Dong-Dong, 2023, Microbial diversity of ticks and a novel typhus group Rickettsia species (Rickettsiales bacterium Ac 37 b) in Inner Mongolia, China, pp.
Su, Si, Hong, Mei, Cui, Meng-Yu, Gui, Zheng, Ma, Shi-Fa, Wu, Lin, Xing, Li-Li, Mu, Lan, Yu, Jing-Feng, Fu, Shao-Yin, Gao, Rui-Juan, Qi, Dong-Dong   +11 more
openaire   +2 more sources

Genomic changes during the evolution of the Coxiella genus along the parasitism-mutualism continuum

Peer Community Journal, 2023
The Coxiellaceae family is composed of five genera showing lifestyles ranging from free-living to symbiosis. Among them, Coxiella burnetii is a well-known pathogen causing Q fever in humans.
Santos-Garcia, Diego, Morel, Olivier, Henri, Hélène, El Filali, Adil, Buysse, Marie, Noël, Valérie, McCoy, Karen D., Gottlieb, Yuval, Klasson, Lisa, Zenner, Lionel, Duron, Olivier, Vavre, Fabrice   +11 more
doaj   +1 more source

Contributions of lipopolysaccharide and the type IVB secretion system to Coxiella burnetii vaccine efficacy and reactogenicity

npj Vaccines, 2021
Coxiella burnetii is the bacterial causative agent of the zoonosis Q fever. The current human Q fever vaccine, Q-VAX®, is a fixed, whole cell vaccine (WCV) licensed solely for use in Australia. C.
Carrie M. Long, Paul A. Beare, Diane C. Cockrell, Jonathan Fintzi, Mahelat Tesfamariam, Carl I. Shaia, Robert A. Heinzen   +6 more
doaj   +1 more source

Coxiella burnetii Sterol-Modifying Protein Stmp1 Regulates Cholesterol in the Intracellular Niche

mBio, 2022
Coxiella burnetii replicates in a phagolysosome-like vacuole called the Coxiella-containing vacuole (CCV). While host cholesterol readily traffics to the CCV, cholesterol accumulation leads to CCV acidification and bacterial death.
Tatiana M. Clemente, Rochelle Ratnayake, Dhritiman Samanta, Leonardo Augusto, Paul A. Beare, Robert A. Heinzen, Stacey D. Gilk   +6 more
doaj   +1 more source

Identification of OmpA, a Coxiella burnetii protein involved in host cell invasion, by multi-phenotypic high-content screening. [PDF]

PLoS Pathogens, 2014
Coxiella burnetii is the agent of the emerging zoonosis Q fever. This pathogen invades phagocytic and non-phagocytic cells and uses a Dot/Icm secretion system to co-opt the endocytic pathway for the biogenesis of an acidic parasitophorous vacuole where ...
Eric Martinez, Franck Cantet, Laura Fava, Isobel Norville, Matteo Bonazzi   +4 more
doaj   +1 more source

Phylogeography of Human and Animal Coxiella burnetii Strains: Genetic Fingerprinting of Q Fever in Belgium

Frontiers in Cellular and Infection Microbiology, 2021
Q fever is a zoonotic disease caused by the bacteria Coxiella burnetii. Domestic ruminants are the primary source for human infection, and the identification of likely contamination routes from the reservoir animals the critical point to implement ...
Sara Tomaiuolo, Sara Tomaiuolo, Sara Tomaiuolo, Samira Boarbi, Samira Boarbi, Tiziano Fancello, Tiziano Fancello, Patrick Michel, Patrick Michel, Damien Desqueper, Damien Desqueper, Fabien Grégoire, Jozefien Callens, David Fretin, David Fretin, Bert Devriendt, Eric Cox, Marcella Mori, Marcella Mori   +18 more
doaj   +1 more source

A Coxiella burnetii phospholipase A homolog pldA is required for optimal growth in macrophages and developmental form lipid remodeling

BMC Microbiology, 2018
Background Many gram-negative bacteria produce an outer membrane phospholipase A (PldA) that plays an important role in outer membrane function and is associated with virulence.
Christopher M. Stead, Diane C. Cockrell, Paul A. Beare, Heather E. Miller, Robert A. Heinzen   +4 more
doaj   +1 more source

Typing of Uncultured Isolates of Coxiella burnetii and Coxiella-Like Microorganisms Associated with Ticks Using 16S rRNA Gene Nucleotide Sequence Analysis

Проблемы особо опасных инфекций, 2023
The causative agent of Q fever, the intracellular pathogen Coxiella burnetii, is found almost worldwide; many types of blood-sucking ticks that are dangerous to animals and humans are involved in the circulation of the pathogen.
Yu. A. Panferova, N. K. Tokarevich, O. V. Blinova, A. A. Nafeev, E. I. Sibaeva   +4 more
doaj   +1 more source

Dot/Icm Type IVB Secretion System Requirements for Coxiella burnetii Growth in Human Macrophages

mBio, 2011
Central to Q fever pathogenesis is replication of the causative agent, Coxiella burnetii, within a phagolysosome-like parasitophorous vacuole (PV) in mononuclear phagocytes. C.
Paul A. Beare, Stacey D. Gilk, Charles L. Larson, Joshua Hill, Christopher M. Stead, Anders Omsland, Diane C. Cockrell, Dale Howe, Daniel E. Voth, Robert A. Heinzen   +9 more
doaj   +1 more source