Results 121 to 130 of about 3,270,007 (313)

Coxsackievirus B3 and adenovirus infections of cardiac cells are efficiently inhibited by vector-mediated RNA interference targeting their common receptor

open access: yesGene Therapy, 2007
As coxsackievirus B3 (CoxB3) and adenoviruses may cause acute myocarditis and inflammatory cardiomyopathy, isolation of the common coxsackievirus–adenovirus-receptor (CAR) has provided an interesting new target for molecular antiviral therapy.
H. Fechner   +12 more
semanticscholar   +1 more source

Molecular identification of viral agents associated with acute conjunctivitis: a prospective controlled study

open access: yesBrazilian Journal of Infectious Diseases, 2017
Background: Viral conjunctivitis are the most frequent infections in ophthalmology clinics. The diagnosis is usually relying on clinical findings and medical history.
Emine Akçay   +8 more
doaj   +1 more source

Atomic structures of Coxsackievirus A6 and its complex with a neutralizing antibody

open access: yesNature Communications, 2017
Coxsackievirus A6 (CVA6) has recently emerged as a major cause of hand, foot and mouth disease in children worldwide but no vaccine is available against CVA6 infections.
Longfa Xu   +22 more
semanticscholar   +1 more source

Acute hemorrhagic conjunctivitis epidemic in São Paulo State, Brazil, 2011

open access: yesRevista Panamericana de Salud Pública
Acute hemorrhagic conjunctivitis (AHC) infection is highly contagious and can lead to explosive epidemics. In early February 2011, the Center for Epidemiologic Surveillance of the State of São Paulo Health Secretariat (SES-SP) in Brazil received reports ...
Norma H. Medina   +6 more
doaj  

Minimal hepatic toxicity of Onyx-015: spatial restriction of coxsackie-adenoviral receptor in normal liver. [PDF]

open access: yes, 2007
We administered an adenoviral vector, Onyx-015, into the hepatic artery of patients with metastatic colorectal cancer involving the liver. Thirty-five patients enrolled in this multi-institutional phase I/II trial received up to eight arterial infusions ...
Au, T   +5 more
core  

TRIM21 Restricts Coxsackievirus B3 Replication, Cardiac and Pancreatic Injury via Interacting With MAVS and Positively Regulating IRF3-Mediated Type-I Interferon Production

open access: yesFrontiers in Immunology, 2018
Tripartite motif-containing 21 (TRIM21) is a regulator of tissue inflammation and pro-inflammatory cytokine production, and has been implicated in negative regulation of IRF3-dependent type I interferon signaling.
Hui Liu, Min Li, Yahui Song, Wei Xu
semanticscholar   +1 more source

Circumventing antivector immunity: potential use of nonhuman adenoviral vectors [PDF]

open access: yes, 2014
Adenoviruses are efficient gene delivery vectors based on their ability to transduce a wide variety of cell types and drive high-level transient transgene expression. While there have been advances in modifying human adenoviral (HAdV) vectors to increase
Beard C.W.   +30 more
core   +3 more sources

Coxsackievirus B4 Transplacental Infection Severely Disturbs Central Tolerogenic Mechanisms in the Fetal Thymus [PDF]

open access: gold, 2021
Aymen Halouani   +10 more
openalex   +1 more source

Development and evaluation of reverse transcription-loop-mediated isothermal amplification assay for rapid detection of enterovirus 71

open access: yesBMC Infectious Diseases, 2011
Background Hand, foot, and mouth disease (HFMD) caused by enterovirus 71 (EV71) is very common in China. It is difficult to distinguish between EV71 and coxsackievirus A16 (CVA16) infections in clinical HFMD patients. Routine laboratory diagnosis of EV71
Shi Mei   +5 more
doaj   +1 more source

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