Results 71 to 80 of about 20,829 (225)

Coxsackievirus B3 Activates Macrophages Independently of CAR-Mediated Viral Entry

Viruses
Enteroviruses are a genus of small RNA viruses that are responsible for approximately one billion global infections annually. These infections range in severity from the common cold and flu-like symptoms to more severe diseases, such as viral myocarditis,
Yasir Mohamud, Jingfei Carly Lin, Sinwoo Wendy Hwang, Amirhossein Bahreyni, Zhihan Claire Wang, Honglin Luo   +5 more
doaj   +1 more source

Calcium signals and calpain-dependent necrosis are essential for release of coxsackievirus B from polarized intestinal epithelial cells [PDF]

, 2011
Coxsackievirus B (CVB), a member of the enterovirus family, targets the polarized epithelial cells lining the intestinal tract early in infection. Although the polarized epithelium functions as a protective barrier, this barrier is likely exploited by ...
Bergelson, JM, Bozym, RA, Cheung, KH, Coyne, CB, Morosky, SA, Patel, K, White, C   +6 more
core   +1 more source

Human Astrocytic Cells Support Persistent Coxsackievirus B3 Infection [PDF]

Journal of Virology, 2013
ABSTRACT Enteroviruses can frequently target the human central nervous system to induce a variety of neurological diseases. Although enteroviruses are highly cytolytic, emerging evidence has shown that these viruses can establish persistent infections both in vivo and in vitro ...
Xiaowei, Zhang, Zhenhua, Zheng, Bo, Shu, Xijuan, Liu, Zhenfeng, Zhang, Yan, Liu, Bingke, Bai, Qinxue, Hu, Panyong, Mao, Hanzhong, Wang   +9 more
openaire   +2 more sources

Negative Correlation Between Serum Ferritin and CD4+ Lymphocytes: A Retrospective Study on Kikuchi‐Fujimoto Disease

Immunity, Inflammation and Disease, Volume 14, Issue 2, February 2026.
This retrospective cohort study indicates that patients with Kikuchi–Fujimoto disease demonstrated immunosuppression characterized by decreased counts of circulating CD3+ and CD4+ lymphocytes. Moreover, serum ferritin levels were inversely correlated with CD4+ lymphocyte counts, suggesting a potential role of ferritin in immune dysregulation in Kikuchi–
Peng Zhong, Xiwen Sang, Yu Yang, Zhenzhou Wang   +3 more
wiley   +1 more source

Interactions between enteroviruses and the host : implications for type 1 diabetes [PDF]

, 2014
Type 1 diabetes (T1D) is a disease that results after a selective destruction of the insulin-producing β-cells in the pancreas. The lack of β-cells renders T1D patients completely unable to synthesize and secrete insulin, which leads to a life-long ...
Larsson, Pär
core   +1 more source

Polyethylene Terephthalate Micro and Nanoplastics Induce Oxidative and Endoplasmic Reticulum Stress, Compromising Intestinal Epithelial Integrity and Viability

Allergy, EarlyView.
Sena Ardicli, Huseyn Babayev, Lihong Chang, Ozge Ardicli, Can Zeyneloglu, Yagiz Pat, Duygu Yazici, Xiaoqing Liu, Ezgi Irem Bektas, Carina Beha, Halil I. Akyildiz, Nazrin B. Mammadova, Muhammed Emin Sari, Beate Rückert, Raja Dhir, Ismail Ogulur, Kari C. Nadeau, Mubeccel Akdis, Cezmi A. Akdis   +18 more
wiley   +1 more source

Progress in RNA‐Targeted Therapeutics for Human Diseases

MedComm, Volume 7, Issue 2, February 2026.
RNA‐targeted therapies are revolutionizing molecular medicine by transitioning from a “protein‐centric” focus to an “RNA‐regulatory network” approach. Leveraging RNA's diverse roles in gene regulation, signaling, and epigenetic modifications, advanced platforms such as ASOs, siRNA, miRNA, mRNA, aptamers, shRNA, and CRISPR/Cas systems are enabling ...
Wangzheqi Zhang, Aimin Jiang, Bin‐Kui Jia, Yuming Jin, Yinghu Chen, Zhaoyu Li, Yan Liao, Haoling Zhang, Zhiheng Lin, Xiao Fang, Linhui Wang   +10 more
wiley   +1 more source

NLRP3-dependent pyroptosis exacerbates coxsackievirus A16 and coxsackievirus A10-induced inflammatory response and viral replication in SH-SY5Y cells

Virus Research
Coxsackievirus A16 (CV-A16) and coxsackievirus A10 (CV-A10), more commonly etiological agents of hand, foot and mouth disease (HFMD), are capable of causing severe neurological syndromes with high fatalities, but their neuropathogenesis has rarely been ...
Yajie Hu, Wei Zhao, Yaming Lv, Hui Li, Jiang Li, Mingmei Zhong, Dandan Pu, Fuping Jian, Jie Song, Yunhui Zhang   +9 more
doaj   +1 more source

Gender and Age Trends of the Coxsackievirus: A Retrospective Study of a Pediatric Practice [PDF]

, 2014
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Curley, Kara L, Smith, Jimmy C, Ph.D
core   +1 more source

Prevention of In‐Stent Restenosis After PCI by Saponin Natural Products: Inhibition of Platelet Activation

Journal of Cellular and Molecular Medicine, Volume 30, Issue 3, February 2026.
ABSTRACT Percutaneous coronary intervention (PCI) enables coronary revascularisation and restores haemodynamic stability but also carries risks of delayed complications including in‐stent restenosis (ISR), a chronic progressive disease with endovascular damage after PCI, which compromises the long‐term efficacy of PCI.
Xueli Lei, Chunlei Lv, Yu Zhang, Zhiyu Li, Hao Shen, Li Zhu   +5 more
wiley   +1 more source