Results 1 to 10 of about 325,498 (98)
Frontiers in Cell and Developmental Biology, 2022 Melanoma, the deadliest type of skin cancer, is on the rise globally. The generally poor prognosis makes melanoma still an enormous public health problem.
Yating Liu +5 more
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MicroRNA-124-3p Plays a Crucial Role in Cleft Palate Induced by Retinoic Acid
Frontiers in Cell and Developmental Biology, 2021 Cleft lip with/without cleft palate (CL/P) is one of the most common congenital birth defects, showing the complexity of both genetic and environmental contributions [e.g., maternal exposure to alcohol, cigarette, and retinoic acid (RA)] in humans ...
Hiroki Yoshioka +4 more
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Nature Structural & Molecular Biology, 2020 Motile cilia power cell locomotion and drive extracellular fluid flow by propagating bending waves from their base to tip. The coordinated bending of cilia requires mechanoregulation by the radial spoke (RS) protein complexes and the microtubule central ...
I. Grossman-Haham +6 more
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Frontiers in Cell and Developmental Biology, 2020 Osteoarthritis (OA) is a chronic degenerative joint disorder associated with degradation and decreased production of the extracellular matrix, eventually leading to cartilage destruction.
M. Jafri +9 more
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Capping protein is essential for cell migration in vivo and for filopodial morphology and dynamics
Molecular Biology of the Cell, 2014 This study shows that capping protein (CP) is essential for mammalian cell migration in vitro and in vivo. The authors also show that CP is present in filopodia of multiple cell types and that it regulates filopodial structure and function.
S. Sinnar +4 more
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Frontiers in Cell and Developmental Biology, 2021 The Arp2/3 complex generates branched actin networks at different locations of the cell. The WASH and WAVE Nucleation Promoting Factors (NPFs) activate the Arp2/3 complex at the surface of endosomes or at the cell cortex, respectively. In this review, we
A. Fokin, A. Gautreau
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Translational Diffusion of Macromolecule-sized Solutes in Cytoplasm and Nucleus
Journal of Cell Biology, 1997 Fluorescence recovery after photobleaching (FRAP) was used to quantify the translational diffusion of microinjected FITC-dextrans and Ficolls in the cytoplasm and nucleus of MDCK epithelial cells and Swiss 3T3 fibroblasts. Absolute diffusion coefficients
O. Seksek, J. Biwersi, A. Verkman
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Acta Crystallographica. Section F : Structural Biology and Crystallization Communications, 2010 As part of the life cycle of the pneumococcal phage Cp-7, the endolysin Cpl-7 cleaves the glycosidic beta1,4 bonds between N-acetylmuramic acid and N-acetylglucosamine in the pneumococcal cell wall, resulting in bacterial lysis.
N. Silva-Martín +5 more
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Twinfilin uncaps filament barbed ends to promote turnover of lamellipodial actin networks
Nature Cell Biology, 2019 Coordinated polymerization of actin filaments provides force for cell migration, morphogenesis and endocytosis. Capping protein (CP) is a central regulator of actin dynamics in all eukaryotes.
Markku Hakala +6 more
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Sonic Hedgehog promotes proliferation of Notch-dependent monociliated choroid plexus tumour cells
Nature Cell Biology, 2016 Aberrant Notch signalling has been linked to many cancers including choroid plexus (CP) tumours, a group of rare and predominantly paediatric brain neoplasms.
Li Li +12 more
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