Results 11 to 20 of about 325,498 (98)

Microtubule-bundling protein Spef1 enables mammalian ciliary central apparatus formation

Journal of Molecular Cell Biology, 2019
Cilia are cellular protrusions containing nine microtubule (MT) doublets and function to propel cell movement or extracellular liquid flow through beating or sense environmental stimuli through signal transductions.
Jianqun Zheng, Hao Liu, Lei Zhu, Yawen Chen, Huijie Zhao, Wei Zhang, Fan Li, Lele Xie, Xiumin Yan, Xueliang Zhu   +9 more
semanticscholar   +1 more source

Enjoy the Silence: Nearly Half of Human tRNA Genes Are Silent

Bioinformatics and Biology Insights, 2019
Transfer RNAs (tRNAs) are key components of the translation machinery. They read codons on messenger RNAs (mRNAs) and deliver the appropriate amino acid to the ribosome for protein synthesis.
A. G. Torres
semanticscholar   +1 more source

Anastral meiotic spindle morphogenesis: role of the non-claret disjunctional kinesin-like protein

Journal of Cell Biology, 1996
We have used time-lapse laser scanning confocal microscopy to directly examine microtubule reorganization during meiotic spindle assembly in living Drosophila oocytes.
H. J. Matthies, H. McDonald, L. Goldstein, W. Theurkauf   +3 more
semanticscholar   +1 more source

CARMIL family proteins as multidomain regulators of actin-based motility

Molecular Biology of the Cell, 2017
CARMILs are large multidomain proteins that regulate the actin-binding activity of capping protein (CP), a major capper of actin filament barbed ends in cells.
B. Stark, M. H. Lanier, J. Cooper
semanticscholar   +1 more source

Chlamydomonas reinhardtii hydin is a central pair protein required for flagellar motility

Journal of Cell Biology, 2007
Mutations in Hydin cause hydrocephalus in mice, and HYDIN is a strong candidate for causing hydrocephalus in humans. The gene is conserved in ciliated species, including Chlamydomonas reinhardtii. An antibody raised against C.
K. Lechtreck, G. Witman
semanticscholar   +1 more source

Three-Dimensional Spatiotemporal Modeling of Colon Cancer Organoids Reveals that Multimodal Control of Stem Cell Self-Renewal is a Critical Determinant of Size and Shape in Early Stages of Tumor Growth

Bulletin of Mathematical Biology, 2018
Huaming Yan, A. Konstorum, J. Lowengrub
semanticscholar   +1 more source

Suppression of B-RafV600E melanoma cell survival by targeting mitochondria using triphenyl-phosphonium-conjugated nitroxide or ubiquinone

Cancer Biology & Therapy, 2017
Seung-Keun Hong, D. Starenki, Pui-Kei Wu, Jong-In Park   +3 more
semanticscholar   +1 more source

CD2AP Links Cortactin and Capping Protein at the Cell Periphery To Facilitate Formation of Lamellipodia

Molecular and Cellular Biology, 2012
Jian-ping Zhao, Serawit Bruck, S. Cemerski, Lei Zhang, B. Butler, Adish Dani, J. Cooper, A. Shaw   +7 more
semanticscholar   +1 more source

The Mutant p53-Conformation Modifying Drug, CP-31398, Can Induce Apoptosis

Cancer Biology & Therapy, 2002
R. Takimoto, Wenge Wang, D. Dicker, F. Rastinejad, J. Lyssikatos, W. El-Deiry   +5 more
semanticscholar   +1 more source

Stabilization of p53 by CP-31398 Inhibits Ubiquitination without Altering Phosphorylation at Serine 15 or 20 or MDM2 Binding

Molecular and Cellular Biology, 2003
Wenge Wang, R. Takimoto, F. Rastinejad, W. El-Deiry   +3 more
semanticscholar   +1 more source