Results 101 to 110 of about 51,179 (262)

Membrane‐Permeable Nucleoside T‐1106 Diphosphate and Triphosphate Analogues as Antiviral Pronucleotides

open access: yesChemistry – A European Journal, EarlyView.
Favipiravir (T‐705) and the non‐fluorinated counterpart (T‐1106) are antiviral agents that inhibit the RNA‐dependent RNA polymerase (RdRp) of various RNA viruses. The antiviral efficacy of nucleoside analogues is strongly dependent on their intracellular activation by cellular kinases to produce their corresponding triphosphate metabolites (T‐705‐RTP ...
Chris Meier   +7 more
wiley   +1 more source

4′‐ThioRNA Substitution and Sense‐Strand Segmentation for the Design of Functional Fully Modified siRNAs Targeting SARS‐CoV‐2

open access: yesChemistry – A European Journal, EarlyView.
4′‐ThioRNA was broadly tolerated across multiple positions in SARS‐CoV‐2‐targeting siRNAs, but full 4'‐thio modification of both strands caused a reduction in RNAi activity. Sense‐strand segmentation improved RNAi and antiviral activity, particularly when the nick was located at position 10 from the 5′‐end of the sense strand, thereby unlocking the ...
Yuhei Nogi   +5 more
wiley   +1 more source

Experimental methods in chemical engineering: Cyclic voltammetry—CV

open access: yesThe Canadian Journal of Chemical Engineering, EarlyView.
Abstract Cyclic voltammetry (CV) is a foundational electroanalytical technique for investigating redox behaviour and evaluating material performance across fields such as molecular electrochemistry, electrocatalysis, sensing, and energy storage. Despite its widespread use, a gap remains between formal electrochemical theory and the practical data ...
Yasser Matos‐Peralta   +4 more
wiley   +1 more source

Feasibility Study of Basic Steel Slag as Anode of Li‐Ion Batteries

open access: yesCleanMat, EarlyView.
This study presents a low‐cost, eco‐friendly approach to utilize basic steel slag as a sustainable anode for lithium‐ion batteries, demonstrating good cyclic stability, rate capability, and long‐term electrochemical performance. ABSTRACT The elevated expenses and utilization of hazardous chemicals in traditional chemical synthesis of anode materials of
Rudra Barua   +2 more
wiley   +1 more source

Synergistic Crystallinity Reduction and Lewis Acidic Promotion by PVDF‐Al(OH)3 for High Room‐Temperature Ionic Conductivity in PEO‐Based Composite Quasi‐Solid Electrolytes

open access: yesEcoEnergy, EarlyView.
Through the synergistic effects of crystallinity reduction and Lewis acidic promotion enabled by PVDF‐Al(OH)3, a PEO‐based composite quasi‐solid electrolyte has been developed, achieving both a high Li+ transfer number and superior ionic conductivity. It endows lithium metal batteries with excellent cycling stability at room temperature, even without ...
Kongmei Chen   +10 more
wiley   +1 more source

Effect of Sequential and Combined Space‐Based Stressors on Perovskite Solar Cell Stability

open access: yesEcoEnergy, EarlyView.
A correlation between loss in performance and mobile ion concentration has been established by sequential stressing of perovskite solar cells under Low Earth Orbit conditions with exposure to protons, light, and thermal cycling. It is shown that the loss in performance increases when ion concentration increases and vice versa.
Saivineeth Penukula   +9 more
wiley   +1 more source

Machine Learning‐Assisted Design of BaTiO3‐Based Superparaelectric High‐Entropy Ceramics with Superior Energy Storage

open access: yesENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
This study employed an adaptive iterative strategy combining machine learning algorithms, domain knowledge, experimental design, and experimental feedback to aim to precisely and quickly discover high‐entropy ceramics with excellent energy storage performance.
Haowen Liu   +4 more
wiley   +1 more source

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