Results 11 to 20 of about 21,509 (233)

Antioxidant and Anti-Inflammatory Potential of Thymoquinone and Lycopene Mitigate the Chlorpyrifos-Induced Toxic Neuropathy

Pharmaceuticals, 2021
CPF (chlorpyrifos) is an organophosphate pesticide used in agricultural and veterinary applications. Our experiment aimed to explore the effects of thymoquinone (TQ) and/or lycopene (LP) against CPF-induced neurotoxicity.
Mohamed Aboubakr, Said M. Elshafae, Ehab Y. Abdelhiee, Sabreen E. Fadl, Ahmed Soliman, Afaf Abdelkader, Mohamed M. Abdel-Daim, Khaled A. Bayoumi, Roua S. Baty, Enas Elgendy, Amira Elalfy, Bodour Baioumy, Samah F. Ibrahim, Ahmed Abdeen   +13 more
doaj   +1 more source

Pterostilbene Alleviates Chlorpyrifos-Induced Damage During Porcine Oocyte Maturation

Frontiers in Cell and Developmental Biology, 2021
Chlorpyrifos (CPF), a widely used organophosphate pesticide, is reported to severely impair mammalian reproductive system. Pterostilbene (PTS), an effective free radical scavenger, is considered as beneficial for mammalian reproduction.
Lili Guo, Lili Guo, Yongda Zhao, Yanjun Huan   +3 more
doaj   +1 more source

First‐Line Osimertinib in Patients with EGFR‐Mutant Advanced Non‐Small Cell Lung Cancer: Outcome and Safety in the Real World: FLOWER Study

The Oncologist, EarlyView., 2021
Abstract Lessons Learned Osimertinib has confirmed effectiveness in this real‐world population of patients with EGFR‐mutant advanced non‐small cell lung cancer. Thromboembolic events occur more frequently than previously reported, suggesting a thrombotic diathesis that requires further investigation. Patients with at least three metastatic sites, brain
Martina Lorenzi, Alessandra Ferro, Fabiana Cecere, Daniela Scattolin, Alessandro Del Conte, Alessandro Follador, Sara Pilotto, Valentina Polo, Mariacarmela Santarpia, Rita Chiari, Alberto Pavan, Alessandro Dal Maso, Valentina Da Ros, Giada Targato, Sabrina Vari, Stefano Indraccolo, Fiorella Calabrese, Stefano Frega, Laura Bonanno, Pier Franco Conte, Valentina Guarneri, Giulia Pasello   +21 more
wiley   +1 more source

Lateral hypothalamic melanin concentrating hormone-expressing neurons both promote and are required for cue-potentiated feeding. [PDF]

J Neuroendocrinol
Abstract Food‐related stimuli can promote feeding behaviors independent of metabolic need. Cue‐potentiated feeding (CPF) studies in rodents offer the potential to reveal the psychobiological mechanisms underlying learned overeating behaviors. We examined whether lateral hypothalamic area (LHA) cells expressing the feeding signal Melanin Concentrating ...
Raycraft LM, Mo B, Doneth A, Lee-Tanner J, Johnson AW.   +4 more
europepmc   +2 more sources

Anti-Hyperglycemic Effects of Refined Fractions from Cyclocarya paliurus Leaves on Streptozotocin-Induced Diabetic Mice

Molecules, 2021
To identify the chemical components responsible for the anti-hyperglycemic effect of Cyclocarya paliurus (Batal.) Iljinsk (Juglandaceae) leaves, an ethanol extract (CPE) and a water extract (CPW) of C.
Zheling Feng, Zhujun Fang, Cheng Chen, Chi Teng Vong, Jiali Chen, Ruohan Lou, Maggie Pui Man Hoi, Lishe Gan, Ligen Lin   +8 more
doaj   +1 more source

PENINGKATAN STABILITAS TEGANGAN STATIS DENGAN PENEMPATAN OPTIMAL STATCOM PADA SISTEM KELISTRIKAN BALI 16-BUS

Multitek Indonesia, 2020
Ketidakstabilan tegangan terutama terkait dengan ketidakseimbangan daya reaktif. Daya tahan bus dalam sistem daya tergantung pada dukungan daya reaktif yang dapat diterima bus dari sistem.
Ni Putu Agustini, I Made Wartana
doaj   +1 more source

Impact of chronic exposure to the pesticide chlorpyrifos on respiratory parameters and sleep apnea in juvenile and adult rats. [PDF]

PLoS ONE, 2018
The widely used organophosphorus pesticide chlorpyrifos (CPF) is often detected in food. CPF inhibits acetylcholinesterase and can modify muscle contractility and respiratory patterns.
Walaa Darwiche, Jérôme Gay-Quéheillard, Stéphane Delanaud, Hiba El Khayat El Sabbouri, Hassan Khachfe, Wissam Joumaa, Véronique Bach, Wiam Ramadan   +7 more
doaj   +1 more source

Network toxicology study and key target validation of chlorpyrifos-induced nonalcoholic fatty liver disease. [PDF]

Sci Rep
Chlorpyrifos (CPF) is a widely used insecticide known for its extended persistence in soil and water. It can induce non-alcoholic fatty liver disease (NAFLD) in mice.
Li Y, Zhang Z, Li H, Zhang G, Ren J, Gong M, Li H, Sun S, Zhang Y, Li N, Chen X.   +10 more
europepmc   +2 more sources

Fate of chlorpyrifos bound residues in paddy soils: Release, transformation, and phytoavailability

Environment International, 2022
Chlorpyrifos (CPF) is a widely used organophosphorus insecticide that tends to form bound residues (BRs) in soils. However, the stability and biological activity of CPF-BRs remain to be explored.
Jiayin Zhong, Dahang Shen, Hao Li, Yan He, Qian Bao, Wei Wang, Qingfu Ye, Jay Gan   +7 more
doaj   +1 more source

NToxSEM: Enhancing prediction of neurotoxic peptides and neurotoxins using a stacked ensemble-based multimodal framework. [PDF]

Protein Sci
Abstract The safety assessment of therapeutic proteins and genetically modified (GM) organisms relies heavily on the rapid and accurate prediction of peptides, and proteins that exhibit neurotoxic activity. Since experimental methods are time‐consuming and costly, they are not technically suitable for the cost‐effective characterization of neurotoxic ...
Shoombuatong W, Schaduangrat N, Mahmud SMH, Ahmed S.   +3 more
europepmc   +2 more sources