Results 111 to 120 of about 3,204 (205)

Artificial intelligence empowers targeted protein degradation: Core technological innovations, multi‐scenario applications, and translational prospects

Smart Molecules, EarlyView.
AI is transforming TPD by improving the design, prediction, and optimization of degraders such as PROTACs, molecular glues, and LYTACs. This review summarizes key AI‐driven advances, highlights applications across drug discovery stages, and discusses remaining challenges and future directions for accelerating the development of therapies against ...
Shuanglin Qin, Rui Peng, Guangshuai Zhang, Si Yan, Jin Xiao, Zishu Liu, Ziyu Tan, Qingqing Xie, Shangjie Li, Wei Luo, Xiaohe Xiao   +10 more
wiley   +1 more source

Defining Lines of Defense Against Change Propagation Using Cause‐Consequence Analysis

Systems Engineering, EarlyView.
ABSTRACT Complex engineered systems are the core of modern society. So that engineered systems and infrastructure can be sustainable and offer value over the course of their lifespan, there is a growing need for such systems to be changeable. Yet, establishing and operationalizing changeability can be challenging due to the potential for change ...
Lindsey Jacobson, Scott Ferguson
wiley   +1 more source

Tracking Chain Populations and Branching Structure during Polyethylene Deconstruction Processes

ACS Central Science
Alex H. Balzer, Zachary R. Hinton, Brandon C. Vance, Dionisios G. Vlachos, LaShanda T. J. Korley, Thomas H. Epps   +5 more
doaj   +1 more source

ESG Performance, Green Finance Activities, and Bank Financial Stability: The Role of Institutional Quality

Thunderbird International Business Review, EarlyView.
ABSTRACT This study investigates the relationship between Environmental, Social, and Governance (ESG) performance and bank financial stability within the context of the green finance transition. Utilizing an unbalanced panel dataset of 251 banks across 56 countries, observed over the period 2009–2024, we analyze how this relationship is moderated by ...
Imen Fakhfakh, Amal Ghribi, Soulef Smaoui   +2 more
wiley   +1 more source

Exchange‐Rate Responses to Structural Oil‐Market Shocks: Revisiting Krugman's Real–Financial Adjustment Framework

Australian Economic Papers, EarlyView.
ABSTRACT This study examines how structural oil‐market shocks affect exchange rates through the real and financial adjustment mechanisms proposed by Krugman (1983). Using a two‐stage SVAR–ARDL/NARDL framework, we identify oil supply, aggregate demand, and oil‐specific demand shocks and estimate their symmetric and asymmetric effects for oil‐importing ...
Jungho Baek, Min‐Joon Kim
wiley   +1 more source

Beyond Inflation: The Adequacy of Out‐of‐Home Care Allowances in Australia

Australian Economic Review, EarlyView.
ABSTRACT Research Question This study examines whether home‐based (foster, kinship or relative) out‐of‐home care (OOHC) allowances in New South Wales, Australia, adequately reflect the contemporary costs of caring for children. Research Findings We find that real median expenditure among families with children increased by 23%–30% between 2006 and 2022,
Ou Yang, Ron Fisher, Karinna Saxby, Jongsay Yong, Yuting Zhang   +4 more
wiley   +1 more source

Alternative Contract Design: Analysing the Bankability of Fungible Derivative Contracts in Energy‐Only Markets

Australian Journal of Agricultural and Resource Economics, EarlyView.
ABSTRACT With the retirement of 21GW of legacy coal fleet looming, the task to replace Australia's thermal capacity with alternative firmed renewable ‘bulk energy’ solutions is non‐trivial. Indeed, calibrating necessary capital investment in new plant stock with efficient economic outcomes, vis‐à‐vis cost and reliability, represents a fundamental ...
Nicholas Gohdes, Tim Nelson, Phillip Hirschhorn   +2 more
wiley   +1 more source

The Value of Controlling Wilding Conifers in New Zealand

Australian Journal of Agricultural and Resource Economics, EarlyView.
ABSTRACT Exotic, invasive conifer tree species, known as ‘wilding conifers’, pose a significant threat to natural ecosystems and are costly to manage, creating a need to identify community preferences in order to inform and balance public investment in their control.
Maksym Polyakov, Abbie Rogers, Philip Stahlmann‐Brown, Rowan Sprague, Olivia Burge, Johanna Yletyinen, Duane A. Peltzer   +6 more
wiley   +1 more source

HOUSING RETROFITS IN JUST TRANSITIONS? Emerging Contradictions in Catalonia, Spain

International Journal of Urban and Regional Research, EarlyView.
Abstract Efforts to decarbonize residential housing are growing globally. Following ambitious targets set by the European Commission's Renovation Wave and subsidized through Covid‐19 recovery funds, Spain's housing retrofit programme deployed EUR 3.4 billion in European grants to retrofit half a million homes between 2022 and 2026.
Melissa García‐Lamarca
wiley   +1 more source

Family Wealth and Wellbeing: The Unequal Distribution of Security Across the Life Course

The British Journal of Sociology, EarlyView.
ABSTRACT Wealth inequality is rising in Australia just as the country enters a period of substantial intergenerational wealth transfer. While wealth is known to be linked to health and wellbeing, we know less about whether parents' wealth continues to matter for wellbeing across adulthood, and through which mechanisms it operates.
Megan Brodie, Brendan Churchill
wiley   +1 more source