Results 91 to 100 of about 116,381 (263)

Establishment of Salivary Gland Tumors Arising in Salivary Gland‐Specific EWSR1::ATF1 Transgenic Mice

Head &Neck, EarlyView.
ABSTRACT Background Salivary gland carcinomas are uncommon malignancies with various histological subtypes harboring fusion genes. The EWSR1::ATF1 fusion gene, resulting from a translocation between chromosomes 12 and 22, is frequently observed in hyalinizing clear cell carcinoma (HCCC). However, the role of this fusion gene in HCCC oncogenesis remains
Yuri Hirai, Yoshitaka Utsumi, Daisuke Sano, Tatsu Kuwahara, Yoshihiro Aizawa, Takashi Hatano, Hisashi Hasumi, Yutaro Soejima, Tatsukata Kawagoe, Ryosuke Jikuya, Nobuhisa Mizuki, Satoshi Fujii, Toshitaka Nagao, Nobuhiko Oridate   +13 more
wiley   +1 more source

Detection and Clinical Significance of Chromosomal Mosaicism in Prenatal Diagnosis: A Retrospective Study From a Prenatal Diagnosis Center

Journal of Clinical Laboratory Analysis, EarlyView.
This retrospective study of 79 prenatal mosaicism cases found that noninvasive prenatal testing (NIPT) had significantly higher sensitivity (90.74%) than first‐ and second‐trimester serum screening, while chromosomal microarray analysis (CMA) showed better concordance with karyotyping (90.00%) than QF‐PCR (58.21%).
Yuanyuan Pei, Xiaojin Luo, Jian Ran, Liang Hu, Weiqiang Liu, Fengxiang Wei   +5 more
wiley   +1 more source

Representation of Long‐Term Observed UK Winter Precipitation Trends and Variability in UKCP18 Global Climate Models

International Journal of Climatology, EarlyView.
Evaluating historical precipitation trends is complicated by interactions between variability in atmospheric circulation and thermodynamic forcing. This study assesses 1901–2023 UK winter precipitation trends in UK Climate Projections 2018 (UKCP18) global climate models using dynamical adjustment to separate circulation‐driven and non‐dynamical ...
James G. Carruthers, Hayley J. Fowler, Daniel Bannister, Selma B. Guerreiro   +3 more
wiley   +1 more source

Effects of Social Capital on Career Development Competency Among Young People With Chronic Disabling Health Conditions: Mediating Role of Chronic Illness Self‐Management

Journal of Employment Counseling, EarlyView.
ABSTRACT This study explores how social capital and chronic illness self‐management influence career development competency among young people with chronic disabling health conditions (YPCDHC) in Hong Kong. Using data from 485 participants aged 15–29, path analysis showed that school/workplace social capital had the strongest positive effects on career
Steven Sek‐yum Ngai, Chau‐kiu Cheung, Yuen‐hang Ng, Pamela Pui‐yu Leung, Mike Kwun‐ting Cheung, Hanlei Du, Haoyi Guo, Yongjia He, Hiu‐lam Ngai, Laing‐ming Wong, Qiushi Zhou   +10 more
wiley   +1 more source

Minced cartilage implantation provides comparable outcomes to autologous chondrocyte implantation (ACI) for knee cartilage lesions: A matched‐pair analysis

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose To compare short‐term patient‐reported outcomes (PROMs) and revision rates between autologous hand‐minced cartilage implantation (MCI) and autologous chondrocyte implantation (ACI) for knee cartilage lesions. Methods All patients undergoing MCI or ACI at a single centre were retrospectively analysed from a prospectively maintained ...
Armin Runer, Louis Leuthard, Luisa Hoheisel, Vincent A. Stadelmann, Stefan Preiss, Gian M. Salzmann, Jakob Hax   +6 more
wiley   +1 more source

Cervical Inlet Patches in R‐CPD: An Unrecognized Predictor of Treatment Failure

The Laryngoscope, EarlyView.
This retrospective cohort study identified cervical inlet patches (CIP) in 19.8% of patients undergoing cricopharyngeal botulinum toxin injection for R‐CPD. CIP presence and increasing age independently predicted failure to sustain a long‐term treatment response, suggesting that CIP may be an underrecognized factor in R‐CPD treatment durability ...
Andrew Geoffrey Tritter, Nabeeha Hasan, Jered Wilson   +2 more
wiley   +1 more source

Comb‐Driven Coherent Optical Transmitter for Scalable DWDM Interconnects

Laser &Photonics Reviews, EarlyView.
A comb‐driven coherent optical transmitter on a Si/SiN platform enables scalable DWDM interconnects by integrating ultra‐compact microring‐assisted modulators and interleavers. High‐baud coherent signaling achieves 400 Gb/s per wavelength and >$>$1 Tb/s multi‐channel transmission, with projected >$>$10 Tb/s per fiber, offering a path toward energy ...
Alireza Geravand, Erwan Weckenmann, Jean‐Michel Vallée, Farshid Shateri, Zibo Zheng, Simon Levasseur, Bo Yang, Jiajian Chen, Ting Wang, Zihao Wang, Leslie A. Rusch, Wei Shi   +11 more
wiley   +1 more source

Proteomic Signatures of Ectopic Fat Distribution: Tissue‐Specific Drivers and Clinical Implications

Med Research, EarlyView.
Integration of plasma proteomics and multi‐organ MRI in 666 UK Biobank participants, combined with a knockoff‐based causal inference and machine learning framework, reveals organ‐specific drivers of ectopic fat: PLA2G1B (pancreas), ERBB2/IGFBP2 (liver), CA14 (muscle), and NCAM2/TNFRSF10B (pericardium). These drivers engage distinct pathways (e.g., PI3K‐
Bing Zhang, Fen Yang, Xingji Lian, Jie He, Shuijin Huang, Mingjuan Fan, Yin Liang, Jiaqiang Huang, LongYan Yin, Hong Wang   +9 more
wiley   +1 more source

Optimization of the Cell‐Based Assay Methodology to Study Degradation of Acetylcholine Receptors (Antigenic Modulation) by Antibodies From Myasthenia Gravis Patients

Muscle &Nerve, EarlyView.
ABSTRACT Introduction/Aims Degradation of cell‐surface acetylcholine receptors (AChRs) by antigenic modulation is a key pathogenic mechanism of myasthenia gravis (MG) autoantibodies, yet standard assays primarily detect antibody binding rather than functional effects.
Peng Du, Marina Mané‐Damas, Fien M. Verhamme, Mahan Moshir, Peter Ulrichts, Barbie Machiels, Mario Losen, Pilar Martinez‐Martinez   +7 more
wiley   +1 more source

Effects of transcranial direct current stimulation on pain and function in patients with knee osteoarthritis: A systematic review and meta‐analysis

PM&R, EarlyView.
Abstract Objective The aim of this systematic review and meta‐analysis is to determine the effects of transcranial direct current stimulation (TDCS) on pain (considering the different types of pain measured) and function in adults with knee osteoarthritis (OA).
Noemí Moreno‐Segura, Sara Mollà‐Casanova, Elena Muñoz‐Gómez, Marta Inglés, Pilar Serra‐Añó   +4 more
wiley   +1 more source