Results 181 to 190 of about 263,382 (282)

Comparative Transcriptomic Analysis of Human Macrophages During Mycobacterium avium Versus Mycobacterium tuberculosis Infection

open access: yesMolecular Microbiology, EarlyView.
Human macrophage transcriptomic responses to Mycobacterium avium (Mav), a major cause of nontuberculous lung disease, were compared to Mycobacterium tuberculosis (Mtb). Both infections activated overlapping immune pathways, including cytokine signaling and GPCRs involved in lipid metabolism, while phospholipases were more strongly regulated by Mav and ...
Gül Kilinç   +4 more
wiley   +1 more source

Genetic Testing for All Breast Cancer Patients: The GET FACTS Randomized Clinical Trial.

open access: yesJAMA Netw Open
Weiss A   +9 more
europepmc   +1 more source

Reduced Descending Itch Inhibition in Peripheral Neuropathy Patients With Chronic Pruritus. [PDF]

open access: yesEur J Pain
Eck J   +9 more
europepmc   +1 more source

Small RNAs regulation and genomic harmony: insights into allopolyploid evolution in marsh orchids (Dactylorhiza)

open access: yesNew Phytologist, EarlyView.
Summary Hybridization and polyploidy are major drivers of plant diversification, often accompanied by shifts in gene expression and genome composition. Small RNAs (smRNAs) are thought to influence such genomic changes, particularly through their interactions with transposable elements (TEs).
Mimmi C. Eriksson   +6 more
wiley   +1 more source

Intact endogenous pain inhibition in complex regional pain syndrome type 1. [PDF]

open access: yesPain Rep
Allmendinger F   +6 more
europepmc   +1 more source

tRF‐30‐FP18LPMBQ4NK in Systemic Juvenile Idiopathic Arthritis: A Promising Diagnostic and Disease Activity Biomarker

open access: yesAnnals of the New York Academy of Sciences, EarlyView.
ABSTRACT Diagnosing systemic juvenile idiopathic arthritis (sJIA) poses significant challenges. Accumulating evidence has indicated that tRNA‐derived fragments (tRFs) play integral roles in the pathogenesis of numerous diseases. Plasma samples were collected from individuals diagnosed with sJIA and healthy controls (HCs) from two medical centers and ...
Jiqian Huang   +6 more
wiley   +1 more source

Referred Pain Manifestation and Its Impact on Patients With Temporomandibular Disorder

open access: yesOral Diseases, EarlyView.
ABSTRACT Objective To investigate whether a higher number of sites eliciting referred pain upon palpation is associated with greater impairment in biopsychosocial aspects in TMD patients and identify variables that predict increased referred pain. Methods This cross‐sectional study analyzed data from 77 women with myalgia, assessing the number of sites
Beatriz Amaral de Lima‐Netto   +5 more
wiley   +1 more source

Incorporation of Temperature Impact on Hot-Carrier Degradation into Compact Physics Model. [PDF]

open access: yesMicromachines (Basel)
Tyaginov S   +9 more
europepmc   +1 more source

Reduced Susceptibility to Phytophthora in Non‐Transgenic Cacao Progeny Through CRISPR–Cas9 Mediated TcNPR3 Mutagenesis

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT Black pod disease, caused by a complex of Phytophthora species, poses a severe threat to global cacao production. This study explores the use of CRISPR–Cas9 genome editing to reduce disease susceptibility in Theobroma cacao L. by targeting the TcNPR3 gene, a known negative regulator of plant defence.
Mark J. Guiltinan   +5 more
wiley   +1 more source

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