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Calcium pyrophosphate deposition (CPPD) disease – Treatment options
Best Practice and Research in Clinical Rheumatology, 2021 In contrast to gout, no disease-modifying therapies currently exist that reduce articular crystal deposition of calcium pyrophosphate crystals (CPPs). Treatment is aimed at ameliorating the inflammatory response and reducing the frequency and severity of clinical symptoms due to CPP deposition (CPPD).
John Stack, Geraldine M Mccarthy
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SLAC WRIST IN THE ABSENCE OF RECOGNISED TRAUMA AND CPPD
Hand Surgery, 2010Purpose: This comparative cohort study was designed to determine whether non-traumatic SLAC wrist exists, and is associated with abnormal carpal bone kinematics (specifically, decreased lunate flexion). Methods: SLAC patients with no recognised history of upper extremity trauma were prospectively compared with an age-matched control group.
J, Pollock +6 more
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Transglutaminase contributes to CPPD crystal formation in osteoarthritis
Frontiers in Bioscience, 2004Calcium pyrophosphate dihydrate (CPPD) crystals are common components of osteoarthritic joints and correlate with a poor prognosis. Transglutaminase (Tgase) enzymes have been implicated in pathologic mineralization in cartilage; yet, definitive studies linking Tgase activity to CPPD crystal formation in osteoarthritic articular cartilage are lacking ...
David, Heinkel +3 more
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2010
Calcium pyrophosphate dihydrate crystal deposition disease (CPPD) and hydroxyapatite crystal deposition disease (HADD) are diseases characterized by deposition of insoluble crystals within the joints and periarticular soft tissues, initiating inflammatory destructive reaction.
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Calcium pyrophosphate dihydrate crystal deposition disease (CPPD) and hydroxyapatite crystal deposition disease (HADD) are diseases characterized by deposition of insoluble crystals within the joints and periarticular soft tissues, initiating inflammatory destructive reaction.
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CPPD complicating other forms of inflammatory arthritis
Clinical Rheumatology, 2006Calcium pyrophosphate deposition (CPPD) disease is confirmed as equally common in rheumatoid arthritis by synovial fluid and macroscopic skeletal examination. Furthermore, differential frequencies in rheumatoid arthritis and spondyloarthropathy provide additional insights to the "lumper-splitter" question.
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CPPD Crystal Deposition Disease or Pseudogout
RadioGraphics, 1982Chondrocalcinosis, arthropathy and joint pain are the hallmarks of the CPPD crystal deposition disease or pseudogout syndrome.
Clyde A. Helms +3 more
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SP0123 How to Evaluate CPPD Using Ultrasound
Annals of the Rheumatic Diseases, 2015Ultrasonography has been increasingly used the last years for the identification of calcium pyrophosphate dihydrate crystal deposition (CPPD) in joints and has demonstrated to be a reliable and feasible tool in most of the studies published. However, it is common experience between sonographers that in daily clinical practice CPP identification by US ...
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Calcium pyrophosphate crystal deposition (CPPD)
2013Calcium pyrophosphate crystal deposition (CPPD) in articular cartilage is a common age-related phenomenon. Recent important advances in our understanding of the pathophysiology of pyrophosphate metabolism include the identification of a mutation within the ANK gene which associates with familial CPPD, and elucidation of the interleukin-1β (IL-1β ...
Edward Roddy, Michael Doherty
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