Results 51 to 60 of about 1,833 (176)

Further Evidence That Chondrocalcinosis 1 (CCAL1) is a Confirmed Mendelian Phenotype With a Known Molecular Basis

American Journal of Medical Genetics Part A, Volume 197, Issue 12, December 2025.
ABSTRACT Chondrocalcinosis (CCAL), also known as calcium pyrophosphate dihydrate deposition disease (CPPDD), is a frequent multifactorial condition in the elderly, but there are two rare autosomal dominant Mendelian forms, CCAL1 (OMIM %600668) and CCAL2. Only three families with molecularly proven CCAL1 have been reported.
Anna‐Christina Pansa, Mareike Selig, Markus Wingendorf, Matthew A. Brown, Oliver Bartsch   +4 more
wiley   +1 more source

Trauma Induced Calcium Pyrophosphate Deposition Disease of the Lumbar Spine

Case Reports in Rheumatology, 2020
Inflammatory arthritis, such as pseudogout or otherwise referred to as calcium pyrophosphate (CPP) crystal arthritis or calcium pyrophosphate deposition (CPPD) disease, is characterized by the deposition of crystal formation and deposition in large ...
Indrit Greca, Jihad Ben Gabr, Andras Perl, Stephanie Bryant, Dan Zaccarini   +4 more
doaj   +1 more source

Clinical Impact of Multiparametric Contrast‐Enhanced Dual‐Energy Computed Tomography in Arthritis Imaging: A Prospective Single‐Center Study

Arthritis &Rheumatology, Volume 77, Issue 12, Page 1655-1662, December 2025.
Objective We aimed to evaluate the influence of contrast‐enhanced dual‐energy computed tomography (CE‐DECT) in detecting and differentiating rheumatic joint diseases of the hand. Methods In this prospective study, patients with suspected arthritis of the hand were investigated consecutively alongside the standard clinical procedure.
Sevtap Tugce Ulas, Jürgen Mews, Sarah Ohrndorf, Robert Biesen, Katharina Ziegeler, Edgar Wiebe, Fabian Proft, Udo Schneider, Denis Poddubnyy, Torsten Diekhoff   +9 more
wiley   +1 more source

Intracellular and extracellular CPPD crystals are a regular feature in synovial fluid from uninflamed joints of patients with CPPD related arthropathy [PDF]

Annals of the Rheumatic Diseases, 2005
To determine whether calcium pyrophosphate dihydrate (CPPD) crystals can be found in the synovial fluid of non-inflamed joints in patients with CPPD related arthropathy; if so, to determine whether they interact with cells and produce subclinical inflammation in this setting.74 synovial fluid samples were obtained from non-inflamed knees of 74 patients
A, Martínez Sanchis, E, Pascual
openaire   +2 more sources

Role of the DPP4 Receptor in SARS‐CoV Entry: Insights From Docking and Molecular Dynamics Simulations

Proteins: Structure, Function, and Bioinformatics, Volume 93, Issue 12, Page 2091-2100, December 2025.
ABSTRACT Protein–receptor interactions play a critical role in viral entry and pathogenesis. While ACE2 is the primary receptor for SARS‐CoV, the role of DPP4 as potential coreceptor remains underexplored. This study investigates the binding mechanisms and dissociation dynamics of the SARS‐CoV/DPP4, SARS‐CoV/ACE2 and MERS‐CoV/DPP4 complexes using ...
Patrícia Pereira Duzi Carvalho, Nelson Augusto Alves   +1 more
wiley   +1 more source

Characterising Alternative Diagnoses to Psoriatic Arthritis in a Rheumatology‐Dermatology Combined Clinic

Australasian Journal of Dermatology, Volume 66, Issue 8, Page 462-467, December 2025.
ABSTRACT Background Psoriatic arthritis (PsA) is a chronic inflammatory arthritis involving axial and peripheral joints and tendons that affects a subset of patients with psoriasis (PsO). PsA can be a debilitating disease and warrants prompt rheumatologic evaluation and management.
Ugochukwu Kingsley Odega, Wilson Omesiete, Adam Carlson, R. Hal Flowers   +3 more
wiley   +1 more source

Calcium pyrophosphate deposition (CPPD) disease: a review of pathophysiology, clinic and diagnosis [PDF]

Exploration of Musculoskeletal Diseases
Calcium pyrophosphate deposition (CPPD) disease represents a crystal-induced arthropathy characterized by the deposition of calcium pyrophosphate dihydrate crystals within the articular joints and adjacent soft tissues.
Gamze Dilek, Mehtap Kalcık Unan, Kemal Nas   +2 more
doaj   +1 more source

Community and School Programs, Policies and Environments Related to Child Dietary Intake:The Healthy Communities Study

Pediatric Obesity, Volume 20, Issue 11, November 2025.
ABSTRACT Background To reverse the epidemic of unhealthy eating and related chronic disease in the United States, intervening early in life is essential. Objective Identify features of community‐ and school‐based programmes, policies and environments related to child intake of fruits and vegetables (FV) and sugar‐sweetened beverages (SSB).
Gail Woodward‐Lopez, Alexander C. McLain, Edward A. Frongillo, Natalie Colabianchi, Vicki Collie‐Akers, Lorrene D. Ritchie   +5 more
wiley   +1 more source

Gout and NLRP3 Inflammasome Biology

Arthritis &Rheumatology, Volume 77, Issue 10, Page 1317-1326, October 2025.
This review describes the three broad stages of acute inflammation in the context of gout: initiation, leucocyte mobilization, and self‐resolution. A typical case of a gout flare is presented. The role of the NLRP3 inflammasome in acute monosodium urate crystal–induced inflammation is reviewed in detail.
Raewyn Poulsen, Nicola Dalbeth
wiley   +1 more source

Cervical Discitis in a 20‐Year‐Old Female: A Case Report

Clinical Case Reports, Volume 13, Issue 10, October 2025.
ABSTRACT Spondylodiscitis, particularly cervical discitis, is a rare infectious condition that can result in severe complications if untreated. This report highlights the rarity of this condition in our female patient's age group and its occurrence in the cervical region in the absence of underlying medical issues. Our article presents a unique case of
Saja Karaja, Ahed Assaf, Shafiq Alassaf, Elias Tannous, Hazem Arab, Mulham Alkassem, Amer Al Tawekji   +6 more
wiley   +1 more source