Results 91 to 100 of about 2,401,111 (345)
Naissance d’un « média jeune » et numérique : une quête d’empowerment sous contrainte
TerminalLe 20 septembre 2017, un établissement culturel situé dans une grande ville du nord de la France, lance un « média jeune » dans le cadre de l’un des Programmes d’investissement d’avenir destiné à la jeunesse, porté par un regroupement de collectivités ...
Coralie Le Caroff +2 more
doaj +1 more source
Private governance in royalty collection: Effectiveness and limitations in tracing GM soybean in Brazil [PDF]
Ce papier analyse l'émergence d'une innovation institutionnelle en accompagnement de la diffusion du soja génétiquement modifié au Brésil. Il en découle une gouvernance plutôt efficace par la création d'une situation gagnant-gagnant pour les acteurs ...
Carlos Magri Ferreira +6 more
core
Ethical Passivity between Maximal and Minimal Meanings [PDF]
, 2016 This paper is a critical review of the most relevant studies about the Levinasian concept of passivity. The purpose is to follow the way in which Levinas’s scholars have dealt with the following aspects: the relation between ethical passivity and the ...
Losada-Sierra, Manuel
core
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
La maternité dans la littérature féminine au Marroc
Lectora: Revista de Dones i Textualitat, 2010 La littérature féminine au Maroc reflète les représentations socio-culturelles de la maternité en la faisant ressortir comme une contrainte imposée aux femmes pour exister dans la société et la famille.
Zohra Mezgueldi
doaj
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Entrepreneurship, Liquidity Constraints and Start-up Costs [PDF]
We study the effects of liquidity constraints and start-up costs on the relationship between wealth and the fraction of entrepreneurs in an economy.
Pierre-Carl Michaud +2 more
core
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
A Systematic Review of Co-Creation and Co-Production: Embarking on the social innovation journey
, 2015 This article presents a systematic review of 122 articles and books (1987–2013) of co-creation/co-production with citizens in public innovation. It analyses (a) the objectives of co-creation and co-production, (b) its influential factors and (c) the ...
W. Voorberg, V. Bekkers, L. Tummers
semanticscholar +1 more source