Results 131 to 140 of about 1,081,549 (235)
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Didactiser la création : entre utopie et réalité
Cet article propose d'articuler utopie et création en revenant sur le processus créateur (Gosselin, 1998; Giacco, Didier & Spampinato, 2017) mis en œuvre dans le cadre d'un projet pédagogique regroupant plusieurs classes dans le canton de VaudDans cette ...
Didier, John
core
Co-creation in research, policy engagement and advocacy: Lessons and limits from two decades of practice at the African Population and Health Research Center. [PDF]
Otukpa EO, Ziraba AK, Bain LE.
europepmc +1 more source
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Vascular Access in Older Adults Approaching Kidney Failure: Is There a Single Right Time? [PDF]
Robinson T, Murea M.
europepmc +1 more source
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Faust-circuit. Une recherche-création sur la recherche création. Texte et dramaturgie de la pièce.
Création: écriture du texte ...
Plana, Muriel
core +1 more source
Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic +15 more
wiley +1 more source
How Generative Artificial Intelligence (GAI) reshapes students' creativity in higher education: A chain path modeling Study from "Exploration-Exploitation" to "Co-Creation-Reflection". [PDF]
Xu J, Zeng Y.
europepmc +1 more source
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source

