Contribution of common and rare variants to bipolar disorder susceptibility in extended pedigrees from population isolates. [PDF]
Current evidence from case/control studies indicates that genetic risk for psychiatric disorders derives primarily from numerous common variants, each with a small phenotypic impact. The literature describing apparent segregation of bipolar disorder (BP)
Sul JH+37 more
europepmc +4 more sources
A complete genome screen for genes predisposing to severe bipolar disorder in two Costa Rican pedigrees. [PDF]
McInnes LA+22 more
europepmc +3 more sources
Kajian Kinerja Alarm Unit Emergency di Ruang Balai Operasi Reaktor [PDF]
Balai operasi reaktor RSG-GAS merupakan ruangan utama dimana terdapat kolam reaktor serta kolam penyimpanan bahan bakar bekas (sementara). Kegiatan pekerjaan dalam ruangan ini selalu ada, baik dalam keadaan reaktor sedang beroperasi maupun sedang tidak ...
Kurniawan, Nazly+2 more
core +2 more sources
Fisetin, a 3,7,3',4'-Tetrahydroxyflavone Inhibits the PI3K/Akt/mTOR and MAPK Pathways and Ameliorates Psoriasis Pathology in 2D and 3D Organotypic Human Inflammatory Skin Models. [PDF]
Psoriasis is a chronic immune-mediated skin disease that involves the interaction of immune and skin cells, and is characterized by cytokine-driven epidermal hyperplasia, deviant differentiation, inflammation, and angiogenesis.
Chamcheu JC+9 more
europepmc +4 more sources
Reconstructing DNA copy number by joint segmentation of multiple sequences [PDF]
The variation in DNA copy number carries information on the modalities of genome evolution and misregulation of DNA replication in cancer cells; its study can be helpful to localize tumor suppressor genes, distinguish different populations of cancerous ...
Lange, Kenneth+2 more
core +4 more sources
Episodic speleothem deposition tracks the terrestrial impact of millennial-scale last glacial climate variability in SW Ireland [PDF]
Eighty four new U-Th ages are presented for twenty randomly selected broken, displaced and reworked calcite speleothems retrieved from clastic sedimentary fill and from isolated bedding-plane shelves in Crag cave (SW Ireland).
Fankhauser, Adelheid+2 more
core +1 more source
ANALISIS KANDUNGAN RADIONUKLIDA PADA GAS BUANG CEROBONG REAKTOR SERBAGUNA G.A. SIWABESSY [PDF]
ANALISIS KANDUNGAN RADIONUKLIDA PADA GAS BUANG CEROBONG REAKTOR SERBAGUNA G.A. SIWABESSY. RSG-GAS adalah reaktor penelitian yang telah berumur lebih dari 30 tahun. Gas buang yang berasal dari dalam gedung dibuang ke lingkungan melalui cerobong dan selalu
Sriyono, Sriyono
core +2 more sources
EVALUASI KESELAMATAN OPERASI REAKTOR RSG-GAS SETELAH 33 TAHUN [PDF]
Keselamatan operasi reaktor RSG-GAS merupakan faktor utama yang menjadi pertimbangan dalam mengoperasikan reaktor. Keselamatan operasi reaktor harus menjamin bahwa parameter neutronik dan termohidraulik teras RSG-GAS tidak melebihi batas keselamatan ...
Pardi, Pardi, Purwadi, Purwadi
core +2 more sources
First Costa Rican record of Pacific Golden-Plover (Pluvialis fulva, Gmelin, 1789) (Aves: Charadriidae) [PDF]
Here we report on the first observation of Pacific Golden Plover in Central America, from Costa Rica.
César Sánchez+2 more
core +1 more source
Circulating exosomes potentiate tumor malignant properties in a mouse model of chronic sleep fragmentation. [PDF]
Background: Chronic sleep fragmentation (SF) increases cancer aggressiveness in mice. Exosomes exhibit pleiotropic biological functions, including immune regulatory functions, antigen presentation, intracellular communication and inter-cellular transfer ...
Khalyfa A+9 more
europepmc +3 more sources