Results 231 to 240 of about 31,583 (288)

Discovery of a Potent Fluorescence Polarization Probe for Identifying USP1 Allosteric Inhibitors

Advanced Science, EarlyView.
This study presents the first ubiquitin‐specific protease 1 (USP1) allosteric fluoroprobe and fluorescence polarization assay, enabling the differentiation of allosteric and catalytic site inhibitors. Further, a novel class of tetrahydroisoquinoline‐based USP1 inhibitors is designed, with compound 14a (USP1 IC50 = 29.9 nM) showing strong selectivity ...
Jiawei Cheng, Peipei Wang, Pengfei Wang, Jiamin Wang, Baiyang Li, Daqing Fang, Jian He, Xiaobei Hu, Weijuan Kan, Yubo Zhou, Chunpu Li, Jia Li, Hong Liu   +12 more
wiley   +1 more source

Fatigue Performance Analysis of Weathering Steel Bridge Decks Under Residual Stress Conditions. [PDF]

Materials (Basel)
Tian W, Li R, Lan T, Gao R, Li M, Liu Q.
europepmc   +1 more source

Fracture Behavior of Steel-Fiber-Reinforced High-Strength Self-Compacting Concrete: A Digital Image Correlation Analysis. [PDF]

Materials (Basel)
Zhang M, Chen J, Liu J, Yin H, Ma Y, Yang F.   +5 more
europepmc   +1 more source

Fracture propagation characteristics in shale bedding planes within structurally complex zones. [PDF]

Sci Rep
Liu X, Zhao L, Li S, Bian X, Zhong G, Yang H, Du X, Li Y.   +7 more
europepmc   +1 more source

Dual-bond fracture metamaterials with full-field extrinsic toughening. [PDF]

Nat Commun
Meng Z, Lei P, Hou B, Liu B, Wang Y.
europepmc   +1 more source

Enhanced Fracture Energy and Toughness of UV-Curable Resin Using Flax Fiber Composite Laminates. [PDF]

Biomimetics (Basel)
Ou M, Li H, Tan D, Peng Y, Zhong H, Wu L, Shan W.   +6 more
europepmc   +1 more source

Research on the Influence of Fibers on the Mechanical Properties of Asphalt Mixtures. [PDF]

Materials (Basel)
Shi Q, Pei Z, Lou K.
europepmc   +1 more source