Results 201 to 210 of about 1,475,288 (355)
Aging Is a Key Driver for Adult Acute Myeloid Leukemia
Aging and Cancer, EarlyView.Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley +1 more source
Study on the Influence of Precipitation Characteristics on Fatigue Properties of Typical 7xxx Aluminum Alloys. [PDF]
Materials (Basel)Tao S +7 more
europepmc +1 more source
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
Aging and Cancer, EarlyView.NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
Visualizing the 3D Evolution and Morphology of Hydrogen-Assisted Ductile Crack Growth in Hydrogen-Precharged P355NH Steel Using X-Ray Micro-Computed Tomography. [PDF]
Materials (Basel)Hell A, Fell J, Werning T, Herrmann HG.
europepmc +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi +2 more
wiley +1 more source
Development and Verification of Crack-Enriched Elements Based on XFEM. [PDF]
Materials (Basel)Shi Y, Chen L, Zhao P, Huo J, Shi L.
europepmc +1 more source
Patterns of Postictal Abnormalities in Relation to Status Epilepticus in Adults
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Abnormalities on peri‐ictal diffusion‐weighted magnetic resonance imaging (DWI‐PMAs) are well‐established for patients with status epilepticus (SE), but knowledge on patterns of DWI‐PMAs and their prognostic impact is sparse. Methods This systematic review and individual participant data meta‐analysis included observational studies ...
Andrea Enerstad Bolle +11 more
wiley +1 more source
Interfacial Friction-Controlled Fiber Failure Modes for Toughness Enhancement of Engineered Cementitious Composites. [PDF]
Materials (Basel)Zhang D, Yang Y, Wang Z, Wang L.
europepmc +1 more source