Results 91 to 100 of about 130,135 (306)

Automatic Pixel-Level Pavement Crack Detection Using Information of Multi-Scale Neighborhoods

open access: yesIEEE Access, 2018
Robust automatic pavement crack detection is critical to automated road condition evaluation. However, research on crack detection is still limited and pixel-level automatic crack detection remains a challenging problem, due to heterogeneous pixel ...
Dihao Ai   +3 more
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

A Novel YOLO Algorithm Integrating Attention Mechanisms and Fuzzy Information for Pavement Crack Detection

open access: yesInternational Journal of Computational Intelligence Systems
Pavement crack detection is widely spread over road maintenance, ensuring the longevity and safety of infrastructure. Traditional manual inspection methods are time-consuming, labor-intensive, and prone to errors.
Qingqing Li   +4 more
doaj   +1 more source

Crack detection using nonlinear output frequency response functions - an experimental study [PDF]

open access: yes, 2006
The new concept of Nonlinear Output Frequency Response Functions (NOFRFs) is introduced in this paper to detect cracks in beams using frequency domain information.
Billings, S.A., Lang, Z.Q., Peng, Z.K.
core  

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Binocular Video-Based Automatic Pixel-Level Crack Detection and Quantification Using Deep Convolutional Neural Networks for Concrete Structures

open access: yesBuildings
Crack detection and quantification play crucial roles in assessing the condition of concrete structures. Herein, a novel real-time crack detection and quantification method that leverages binocular vision and a lightweight deep learning model is proposed.
Liqu Liu   +6 more
doaj   +1 more source

Micro-Touch Detection Using Acoustic Emission Sensor On Inconel 718 [PDF]

open access: yes
An intelligent non-destructive method of monitoring and detecting failures in machining processes is very important. Acoustic Emission (AE) sensors has been used as a non destructive technique in the past for crack and wear detection in workpiece and
Obi, Stanley
core  

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

An improved two-step method based on Kriging model for beam structures

open access: yesJournal of Low Frequency Noise, Vibration and Active Control, 2019
An improved two-step method for multiple cracks detection in beam structures is presented in this paper. First, the crack locations are identified by the mode shape curvatures.
Xie Fengle   +3 more
doaj   +1 more source

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