Results 91 to 100 of about 131,408 (305)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Cracked rotor demonstration [PDF]
The purpose of this demonstration is to observe the behavior of a rotor with a single crack. This will be presented in oscilloscope orbits, 2X POLAR PLOTS, and spectrum cascade diagrams. Crack detection must be observed in all three formats and monitored
Bosmans, R. F.
core +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Statistical Methods for Automatic Crack Detection Based on Vibrothermography Sequence-of-Images Data [PDF]
, 2010 Vibrothermography is a relatively new nondestructive evaluation technique for finding cracks through frictional heat generated from crack surface vibrations under external excitations.
Holland, Stephen +4 more
core +4 more sources
Cracking assessment in concrete structures by distributed optical fiber [PDF]
, 2015 In this paper, a method to obtain crack initiation, location and width in concrete structures subjected to bending and instrumented with an optical backscattered reflectometer (OBR) system is proposed.
Casas Rius, Joan Ramon +2 more
core +2 more sources
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Scientific ReportsTunnel cracks are thin and narrow linear targets, and their pixel proportions in images are usually very low, less than 6%; therefore, a method is needed to better detect small crack targets.
Li Wang, Chao Tang
doaj +1 more source
Automatic Pixel-Level Pavement Crack Detection Using Information of Multi-Scale Neighborhoods
IEEE Access, 2018 Robust automatic pavement crack detection is critical to automated road condition evaluation. However, research on crack detection is still limited and pixel-level automatic crack detection remains a challenging problem, due to heterogeneous pixel ...
Dihao Ai +3 more
doaj +1 more source
Ultrasonic detection and measurement of fatigue cracks in notched specimens [PDF]
Ultrasonic detection and measurement of fatigue crack propagation in notched specimens of aluminum, titanium, and cobalt alloys and maraging ...
Freche, J. C., Klima, S. J.
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source