Results 111 to 120 of about 18,112 (283)

Effectiveness of the Concrete Equivalent Mortar Method for the Prediction of Fresh and Hardened Properties of Concrete

open access: yesBuildings
Modern concrete mix design is a complex process involving superplasticisers, fine powders, and fibres, requiring time and energy due to the high number of trial tests needed to achieve rheological properties in the fresh state. Concrete batching involves
Haruna Ibrahim   +3 more
doaj   +1 more source

Analysis of stevia extract and compare active functional group with other artificial sweetener; aspartame and sucralose [PDF]

open access: yes, 2020
Sugar is very important for everyday use especially for humans as food and drinks as additives. Among all types of sweeteners; sucrose, aspartame and sucralose are widely used in foods and beverage industries.
Ismail, Siti Nur Bahirah   +3 more
core  

A Dual‐Responsive Versatile Nanohybrid Orchestrating Tumor Elimination and Tumor‐Associated Osteolysis Restoration via Sequential Release

open access: yesAdvanced Science, EarlyView.
The versatile CaO2@CuMOF@HAP nanohybrid demonstrates an outstanding MMP9/pH‐triggered release performance for sequential release of osteogenic growth peptide into deep‐seated tumor‐infiltrated bone destruction areas and dual ions into tumor cells, enabling efficient tumor‐associated osteolysis restoration and tumor elimination for more comprehensive ...
Lan Liu   +8 more
wiley   +1 more source

Autoimmune Encephalitis in Acute Care—Pathology, Diagnosis, and Management

open access: yesAdvanced Science, EarlyView.
ABSTRACT Autoimmune encephalitis (AE) is characterized by immune‐mediated inflammation of the brain parenchyma, presenting with various neurological syndromes, including but not limited to seizures, altered consciousness, neuropsychiatric symptoms, and movement disorders.
Suneesh Thilak   +9 more
wiley   +1 more source

Dual‐Responsive Dynamic Covalent Bond‐Based Assembly of Lipid‐Nanozyme Systems via Multi‐Target Synergy and Efficient Target Enrichment for Ischemic Stroke Therapy

open access: yesAdvanced Science, EarlyView.
This system adopts a biomimetic phospholipid structure, covalently binding iNOS inhibitors, neuroprotective agent PCA and vitamin E derivatives through pH/ROS dual‐responsive bonds, and assembles them with Prussian blue nanozyme to form PBB@AHA. It can efficiently penetrate the blood‐brain barrier and simultaneously release multiple active components ...
Mengcheng Guo   +9 more
wiley   +1 more source

Nonlinear Semi-Numeric and Finite Element Analysis of Three-Point Bending Tests of Notched Polymer Fiber-Reinforced Concrete Prisms

open access: yesApplied Sciences
A nonlinear semi-numeric and finite element analysis of three-point bending tests of notched polymer fiber-reinforced concrete prisms was performed. The computational and experimental results were compared in terms of the load-displacement behavior.
Žiga Unuk, Milan Kuhta
doaj   +1 more source

Enzymatic DNA Reaction Networks for Orchestrating Stimuli‐Dependent Temporal Molecular Pulse

open access: yesAdvanced Science, EarlyView.
We present an enzymatic DNA reaction network (EDRN) that encodes nucleic‐acid targets in time, converting inputs into a universal strand and then into programmable transient fluorescence pulses. With time‐color multiplexing, EDRN enables single‐tube high‐plex nucleic acid detection and shows strong agreement with clinical sequencing across 32 specimens.
Jiayu Yang   +7 more
wiley   +1 more source

Analysis of radially cracked ring segments subject to forces and couples [PDF]

open access: yes
Results of planar boundary collocation analysis are given for ring segment (C shaped) specimens with radial cracks, subjected to combined forces and couples. Mode I stress intensity factors and crack mouth opening displacements were determined for ratios
Gross, B., Strawley, J. E.
core   +1 more source

Plant Genetic Engineering: Technological Pathways, Application Scenarios, and Future Directions

open access: yesAdvanced Science, EarlyView.
This review maps the fast‐evolving landscape of plant genetic engineering, linking enabling platforms with trait‐focused applications in architecture optimization, stress resilience, yield improvement, and quality enhancement. It highlights how genome editing, transgenic strategies, and emerging multi‐gene approaches reshape breeding pipelines, while ...
Peilin Wang   +4 more
wiley   +1 more source

Leveraging Artificial Intelligence and Large Language Models for Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
Cancer immunotherapy faces challenges in predicting treatment responses and understanding resistance mechanisms. Artificial intelligence (AI) and machine learning (ML) offer powerful solutions for cancer immunotherapy in patient stratification, biomarker discovery, treatment strategy optimization, and foundation model development.
Xinchao Wu   +4 more
wiley   +1 more source

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