Results 31 to 40 of about 9,934 (302)

Crack Path Prediction in Anisotropic Brittle Materials [PDF]

Physical Review Letters, 2005
A force balance condition to predict quasistatic crack paths in anisotropic brittle materials is derived from an analysis of diffuse interface continuum models that describe both short-scale failure inside a microscopic process zone and macroscopic linear elasticity.
Hakim, Vincent, Karma, Alain
openaire   +3 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Mechanism of crack branching in the fatigue crack growth path of 2324-T39 Aluminium alloy [PDF]

Fracture and Structural Integrity, 2016
The crack growth behavior in 2324-T39 aluminium alloy was experimentally investigated. Two types of crack branching were observed. The mechanism of an uncommon crack branching which results from the link up of secondary crack with the main crack was ...
Lu Songsong, Bao Rui, Zhang Ting, Fei Binjun   +3 more
doaj   +1 more source

Fatigue crack growth rates and paths in two planar specimens under mixed mode loading

, 2016
S.12-19This paper focuses on the evaluation of methods for estimating fatigue crack growth (FCG) under mixed mode I/II loading. The experimental part of the study consists of a series of fatigue crack growth tests on bend and tension specimens with ...
Kadau, K., Burdack, M., Varfolomeev, I., Siegele, D., Moroz, S.   +4 more
core   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Duality of singularities of multiscale damage localization and crack advance: length variety in Theory of Critical Distances

Fracture and Structural Integrity, 2019
The existence of two singularities related to the stress field at the crack tip and blow-up kinetics of damage localization is considered as the physical basis for the interpretation of the Theory of Critical Distances.
Oleg Naimark
doaj   +3 more sources

Mechanics of the crack path formation [PDF]

International Journal of Fracture, 1991
A detailed analysis of experimentally obtained curvilinear crack path trajectories formed in a heterogeneous stress field is presented. Experimental crack path trajectories were used as data for numerical simulations, recreating the actual stress field governing the development of the crack path.
openaire   +1 more source

YlmG1 is localized exclusively to the chloroplast envelope membrane and is involved in preprotein translocation in Arabidopsis thaliana

FEBS Open Bio, EarlyView.
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source

Numerical Analysis of Crack Path Effects on the Vibration Behaviour of Aluminium Alloy Beams and Its Identification via Artificial Neural Networks

Sensors
Understanding and predicting the behaviour of fatigue cracks are essential for ensuring safety, optimising maintenance strategies, and extending the lifespan of critical components in industries such as aerospace, automotive, civil engineering and energy.
Hilal Doğanay Katı, Jamilu Buhari, Arturo Francese, Feiyang He, Muhammad Khan   +4 more
doaj   +1 more source