Results 41 to 50 of about 161,341 (306)

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Effects of pre-cracked width and seawater erosion on the cracking behavior of SFRC beams with BFRP bars subjected to cyclic loading

Developments in the Built Environment
This study aims to explore the effects of various pre-cracked widths, seawater erosion and BFRP reinforcement ratios on the cracking behavior of steel fiber reinforced concrete (SFRC) beams with Basalt Fiber Reinforced Polymer (BFRP) bars subjected to ...
Haitang Zhu, Wencheng Duan, Zongze Li, Zemin Li, Xiangming Zhou, Qingxin Meng   +5 more
doaj   +1 more source

Numerical modelling of non-uniform corrosion induced concrete crack width [PDF]

, 2018
Corrosion of reinforced concrete is one of the major deterioration mechanisms which result in premature failure of the reinforced concrete structures. Crack width is often used as an effective criterion to assess the serviceability of concrete structures.
Li, Chun-Qing, Li, Kefei, Xi, Xun, Yang, Shangtong   +3 more
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Durability and service life of concrete repairs in the presence of cracks [PDF]

, 2010
Engineered Cementitious Composite (ECC) has been proposed to be one of the most promising repair materials due to its unique high ductility and tight crack width control.
van Breugel, Klaas, Ye, Guang, Zhou, Jian   +2 more
core  

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Time and Crack Effect on Chloride Diffusion for Concrete with Fly Ash

International Journal of Concrete Structures and Materials, 2018
Nuclear power plants are constructed very close to the marine environments for cooling water and the structures are more susceptible to chloride induced corrosion.
Sang-Hwa Jung, Hwa-Sung Ryu, Subbiah Karthick, Seung-Jun Kwon   +3 more
doaj   +1 more source

Dynamic evolution and numerical analysis of rock deformation under impact failure based on corner correlation method

Frontiers in Earth Science, 2023
To fulfill the requirement for deformation measurement within the failure area during rock failure, a newly developed digital image algorithm, known as the corner correlation method, was implemented.
Xingui Zhou, Xingui Zhou, Zhongbao Ye, Hong Miao, Wei Li, Xueru Wang, Chenfeng Li   +6 more
doaj   +1 more source

A Robust Adaptive One‐Sample‐Ahead Preview Super‐Twisting Sliding Mode Controller

International Journal of Adaptive Control and Signal Processing, EarlyView.
Block Diagram of the Robust Adaptive One‐Sample‐Ahead Preview Super‐Twisting Sliding Mode Controller. ABSTRACT This article introduces a discrete‐time robust adaptive one‐sample‐ahead preview super‐twisting sliding mode controller. A stability analysis of the controller by Lyapunov criteria is developed to demonstrate its robustness in handling both ...
Guilherme Vieira Hollweg, Paulo Jefferson Dias de Oliveira Evald, Shivam Chaturvedi, Hilton Abilio Gründling, Rodrigo Varella Tambara, Wencong Su   +5 more
wiley   +1 more source

Development of a relationship between external measurements and reinforcement stress [PDF]

, 2015
As many countries around the world face an aging infrastructure crisis, there is an increasing need to develop more accurate monitoring and assessment techniques for reinforced concrete structures. One of the challenges associated with assessing existing
Brault, A, Hoult, NA, Lees, JM
core   +2 more sources