Results 41 to 50 of about 67,160 (268)

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

Mechanical properties of pressure-frozen ice under triaxial compressive stress

open access: yesJournal of Glaciology
Artificial ground freezing is an effective method for underground constructions in deep alluvium. To study the compressive strength of frozen soil under high ground pressure and high hydraulic pressure, it is necessary to understand the mechanical ...
Peixin Sun, Weihao Yang, Jukka Tuhkuri
doaj   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

open access: yesFEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito   +7 more
wiley   +1 more source

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

open access: yesFEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton   +6 more
wiley   +1 more source

Foliar Mineral Treatments for The Reduction of Melon (Cucumis melo L.) Fruit Cracking

open access: yesAgronomy, 2020
Fruit cracking affects many types of crops and is a major problem since the breakage of the surface of the fruit produces high economic losses. Numerous studies have looked at different ways to prevent this, mainly in melon, but with a low success rate ...
Alvaro Lopez-Zaplana   +3 more
doaj   +1 more source

Unravelling the origin of multiple cracking in an additively manufactured Haynes 230

open access: yesMaterials Research Letters, 2023
In this work, by using multi-scale characterizations from electron channeling contrast imaging (ECCI) to atom probe tomography (APT), we directly evidenced that the massive cracking events in the selective-laser-melted (SLMed) Haynes 230 superalloy are ...
Junyang He   +8 more
doaj   +1 more source

Heterotropic regulation and negative homotropic cooperativity

open access: yesFEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea   +5 more
wiley   +1 more source

Database Cracking. [PDF]

open access: yes, 2007
Database indices provide a non-discriminative navigational infrastructure to localize tuples of interest. Their maintenance cost is taken during database updates. In this paper, we study the complementary approach, addressing index maintenance as part of query processing using continuous physical reorganization, i.e., cracking the database into ...
S. Idreos (Stratos)   +2 more
openaire   +2 more sources

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi   +2 more
wiley   +1 more source

Characterization of in situ damage to tungsten PFCs induced by transient heat flux during plasma disruption in EAST

open access: yesNuclear Fusion
Transient heat flux of up to several thousand MW m ^−2 in a short pulse (∼ms) in tokamaks poses great risk to plasma-facing components (PFCs), making it a major concern for ITER.
Chuannan Xuan   +10 more
doaj   +1 more source

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