Expert consensus on clinical trial design guidelines for FLASH radiotherapy
• FLASH radiotherapy has emerged as a transformative technology due to the underlying FLASH effect. • As FLASH radiotherapy moves toward clinical application, establishing standardized trial design principles is critical. • This expert consensus provides a roadmap for rigorous clinical evaluation of FLASH radiotherapy, accelerating safe translation of ...
Hui Luo +9 more
wiley +1 more source
Hippocampal Avoidance During Prophylactic Cranial Irradiation for Patients With Small Cell Lung Cancer: Randomized Phase II/III Trial NRG-CC003. [PDF]
Gondi V +31 more
europepmc +1 more source
Lipid‐coated superparamagnetic iron oxide nanoparticles (LSPIONs) are developed as MRI‐visible lipid nanocarriers for glioblastoma imaging. By tuning nanoparticle size and SPION loading, their transverse relaxivity (r2) can be systematically controlled over one order of magnitude, reaching 390 mm−1 s−1 at 9.4 T.
Marcos Bazarra‐Barreiros +8 more
wiley +1 more source
Retraction: PAK3 downregulation induces cognitive impairment following cranial irradiation.
Lee H, Kang H, Moon C, Youn B.
europepmc +1 more source
Prognostic impact of pan-immune inflammation value in small-cell lung cancer treated with chemoradiotherapy and prophylactic cranial irradiation. [PDF]
Ucgul AN, Hazir H, Bora H.
europepmc +1 more source
ABSTRACT The current study aimed to quantify the antimicrobials amoxicillin (AMX), cefazolin (CFZ), chloramphenicol (CHL), metronidazole (MTZ), and sulfamethoxazole (SX) in effluents and surface water of an important Cerrado river, calculate their half‐lives, and analyze their ecotoxicity following single and combined exposures.
Náthala Maria Simão +12 more
wiley +1 more source
Advance of Prophylactic Cranial Irradiation in Lung Cancer
Kan WU, Bing XIA, Shenglin MA
doaj +1 more source
EDA2R reflects the acute brain response to cranial irradiation in liquid biopsies. [PDF]
Lastra Romero A +4 more
europepmc +1 more source
ABSTRACT Long‐term exposure to low‐dose food contact materials (FCMs) has raised concerns regarding developmental toxicity. In the present study, we prioritized FCMs with potential developmental toxicity using a weight‐of‐evidence computational model, which predicted 127 chemicals to be of high concern.
Chia‐Chi Ho +7 more
wiley +1 more source
Intensity-modulated proton therapy for hippocampal-sparing prophylactic cranial irradiation: a planning comparison with photon therapy. [PDF]
Yin X, Lin X, Zhang G, Yin Y, Sun T.
europepmc +1 more source

