Metabolomic and proteomic stratification of equine osteoarthritis
Abstract Background Equine osteoarthritis (OA) is predominantly diagnosed through clinical examination and radiography, leading to detection only after significant joint pathology. The pathogenesis of OA remains unclear and while many medications modify the disease's inflammatory components, no curative or reversal treatments exist.
James R. Anderson+5 more
wiley +1 more source
The microbiota–gut–brain axis in Huntington's disease: pathogenic mechanisms and therapeutic targets
Disturbances of the microbiota–gut–brain axis are evident in people with Huntington's disease (HD) and in HD animal models. Here, we provide an overview of how the trillions of microorganisms residing in the gut, their secretory products, and the microbiota–gut–brain axis may contribute to HD pathogenesis.
Millicent N. Ekwudo+2 more
wiley +1 more source
Presentation of extranodal NK/T-cell lymphoma as a pituitary mass: A case report and review of the literature. [PDF]
Butler M+10 more
europepmc +1 more source
Headache characteristics in acromegaly: Only a secondary disorder?
Abstract Objective To investigate the characteristics and nature of headache in a population of patients with acromegaly. Background Headache is frequently described by patients with pituitary adenomas. Although it is mainly considered a secondary disorder, it can persist despite effective therapy for pituitary disease. A proper description of headache
Giada Giuliani+6 more
wiley +1 more source
The Neurosurgical Immigrant Experience in Italy: Analysis of a Northeast Tertiary Center. [PDF]
Valenti A+3 more
europepmc +1 more source
Abstract T‐cell re‐directional therapies, including chimeric antigen receptor (CAR)‐T cell and bispecific antibodies (BsA), have transformed the treatment landscape to benefit patients with multiple myeloma. A number of these novel therapies has been approved internationally, with CAR‐T therapy recently approved in Australia.
P. Joy Ho, Eric W. Li
wiley +1 more source
A journey with Maffucci syndrome: From skull base chondrosarcoma to multiorgan management: A case report and literature review. [PDF]
Dibas J+7 more
europepmc +1 more source
Mind the GAPS: Glia associated with psychological stress
Abstract Glial cells are an integral component of the nervous system, performing crucial functions that extend beyond structural support, including modulation of the immune system, tissue repair, and maintaining tissue homeostasis. Recent studies have highlighted the importance of glial cells as key mediators of stress responses across different organs.
Niklas Blank+4 more
wiley +1 more source
A case of orbital tip syndrome caused by sphenoid sinus mucoceles. [PDF]
Fu X, Zhong X, Liang H, Li Y.
europepmc +1 more source
Anatomy of spinal CSF loss in the American alligator (Alligator mississippiensis)
India ink introduced into the cranial cerebrospinal fluid (CSF) compartment of Alligator diffuses along the spinal cord and exits the spinal compartment using perineural flow, resulting in a prominent “ink cuff” forming at the base of the spinal nerve. In Alligator, the region of the ink cuff is drained by a small lymphatic vessel.
Hadyn DeLeeuw+5 more
wiley +1 more source