Results 61 to 70 of about 59,066 (338)

Neural Plasticity and Hearing‐Speech Development in Children with Auditory Brainstem Implants for Congenital Hearing Loss Due to Severe Inner Ear Malformation

open access: yesAdvanced Science, EarlyView.
Data from a prospective cohort with 112 auditory brainstem implant users are analyzed. Younger age at implantation (<3 years), less severe inner‐ear malformation (common cavity, cochlear aplasia, and hypoplasia), and more intraoperative eABR evoked electrodes (≥60%) are associated with better hearing and speech outcomes.
Yu Zhang   +11 more
wiley   +1 more source

The Reconstruction of Peripheral Auditory Circuit: Recent Advances and Future Challenges

open access: yesAdvanced Science, EarlyView.
This paper summarizes the potential of biomaterials, stem cells, and gene editing technologies in the regeneration of inner ear hair cells, spiral ganglion neurons, and inner ear organoids. Challenges and potential developments are discussed and explored.
Zhe Li   +3 more
wiley   +1 more source

Migraine generator network and spreading depression dynamics as neuromodulation targets in episodic migraine [PDF]

open access: yes, 2013
Migraine is a common disabling headache disorder characterized by recurrent episodes sometimes preceded or accompanied by focal neurological symptoms called aura. The relation between two subtypes, migraine without aura (MWoA) and migraine with aura (MWA), is explored with the aim to identify targets for neuromodulation techniques.
arxiv   +1 more source

Unraveling Neurodevelopment: Synergistic Effects of Intrinsic Genetic Programs and Extrinsic Environmental Cues

open access: yesAdvanced Science, EarlyView.
Overview of the regulation of intrinsic and extrinsic signals during neurodevelopment. Intrinsic genetic signals from NSCs, in conjunction with cues from microglia and blood vessels, collaboratively regulate the proliferation of NSCs, their fate determination, synaptogenesis, synaptic pruning, neuronal survival, and death, as well as communication ...
Yanyan Wang   +4 more
wiley   +1 more source

Vocal Fold Paralysis with Intraoperative Recurrent Laryngeal Nerve Identification versus Non-identification of Recurrent Laryngeal Nerve in Total Thyroidectomy: A Retrospective Cohort Study

open access: yesPhilippine Journal of Otolaryngology Head and Neck Surgery, 2016
Objective: To determine the risk of vocal fold paralysis in patients who underwent total thyroidectomy with and without intraoperative recurrent laryngeal nerve identification.
Andrie Jeremy Formanez
doaj   +1 more source

Immunoglobulin G4 hypophysitis in a 63-year-old woman with no autoimmune history: a case report

open access: yesJournal of Medical Case Reports, 2021
Background Immunoglobulin-G4-related hypophysitis is a rare inflammatory disease that can present as a tumefactive pituitary lesion mimicking hypophyseal neoplasms such as pituitary adenoma or craniopharyngioma.
Zachary C. Gersey   +7 more
doaj   +1 more source

Integrating diverse datasets improves developmental enhancer prediction [PDF]

open access: yes, 2013
Gene-regulatory enhancers have been identified by many lines of evidence, including evolutionary conservation, regulatory protein binding, chromatin modifications, and DNA sequence motifs. To integrate these different approaches, we developed EnhancerFinder, a novel method for predicting developmental enhancers and their tissue specificity ...
arxiv   +1 more source

Computational Intelligence Approach to Improve the Classification Accuracy of Brain Neoplasm in MRI Data [PDF]

open access: yesarXiv, 2021
Automatic detection of brain neoplasm in Magnetic Resonance Imaging (MRI) is gaining importance in many medical diagnostic applications. This report presents two improvements for brain neoplasm detection in MRI data: an advanced preprocessing technique is proposed to improve the area of interest in MRI data and a hybrid technique using Convolutional ...
arxiv  

Contemporary management of primary parapharyngeal space tumors [PDF]

open access: yes, 2018
The parapharyngeal space is a complex anatomical area. Primary parapharyngeal tumors are rare tumors and 80% of them are benign. A variety of tumor types can develop in this location; most common are salivary gland neoplasm and neurogenic tumors.
Allison RS   +94 more
core   +2 more sources

Microglial MS4A4A Protects against Epileptic Seizures in Alzheimer's Disease

open access: yesAdvanced Science, EarlyView.
This study has unveiled significant new insights into the role of MS4A4A in Alzheimer's disease‐related epilepsy, highlighting its impact on microglial phagocytosis, mitochondrial metabolism, and cytoskeleton, and demonstrating its therapeutic potential in epilepsy management.
Meng Jiang   +10 more
wiley   +1 more source

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