Results 51 to 60 of about 2,247 (229)

Fibroblast growth factor receptor signaling in hereditary and neoplastic disease: biologic and clinical implications. [PDF]

, 2015
Fibroblast growth factors (FGFs) and their receptors (FGFRs) are transmembrane growth factor receptors with wide tissue distribution. FGF/FGFR signaling is involved in neoplastic behavior and also development, differentiation, growth, and survival.
Helsten, Teresa, Kurzrock, Razelle, Schwaederle, Maria   +2 more
core   +2 more sources

Advanced parental age: Is it contributing to an increased incidence of non-syndromic craniosynostosis? A review of case-control studies

Journal of Oral Biology and Craniofacial Research, 2021
Background: Craniosynostosis (CS) is a congenital birth defect characterized by the premature fusion of one or several calvarial suture(s). CS could lead to serious complications, such as intracranial hypertension and neurodevelopmental impairment. There
Kenzy Abdelhamid, Rea Konci, Hassan ElHawary, Andrew Gorgy, Lee Smith   +4 more
doaj   +1 more source

An exploration of the cognitive, physical and psychosocial development of children with Apert syndrome [PDF]

, 2016
Apert syndrome is a rare condition, with a birth prevalence of approximately 1 in 65 000. This article provides an up to date review of the literature on Apert syndrome from a variety of perspectives, ranging from surgical management to personal accounts.
Hilton, C
core   +1 more source

The Influence of Perioperative Antibiotic Prophylaxis on Wound Infection and on the Colonization of Wound Drains in Patients After Correction of Craniosynostosis

Frontiers in Pediatrics, 2021
Objective: Evidence for the duration of perioperative antibiotic prophylaxis (PAP) after the correction of craniosynostosis in children is scarce. We evaluated the necessary duration of PAP to ensure a minimal rate of postoperative wound infections ...
Johannes Holle, Tobias Finger, Julia Lugonja, Florian Schmidt, Andreas Schaumann, Alexander Gratopp, Ulrich-Wilhelm Thomale, Horst von Bernuth, Horst von Bernuth, Horst von Bernuth, Matthias Schulz   +10 more
doaj   +1 more source

Apert syndrome: the Paris and Rotterdam philosophy [PDF]

, 2017
Introduction: Apert syndrome is a rare type of syndromic craniosynostosis. Patients have an explicit phenotype with craniofacial dysmorphologies and severe symmetrical syndactyly of the hands and feet.
Arnaud, E. (Eric), Bredero-Boelhouwer, H.H. (Hansje), Driessen, C. (Caroline), Joosten, K.F.M. (Koen), Mathijssen, I.M.J. (Irene), Nieuwenhoven, C.A. (Christianne) van, Veelen-Vincent, M.L.C. (Marie-Lise) van, Versnel, S.L. (Sarah), Wolvius, E.B. (Eppo)   +8 more
core   +2 more sources

The utility of molecular genetic techniques in craniosynostosis cases associated with intellectual disability

Romanian Journal of Laboratory Medicine, 2018
Molecular genetic testing in craniosynostosis leads to the detection of the mutations in the genes encoding fibroblast growth factor receptors (FGFR), providing information about the etiology of the genetic disorder.
Bogliş Alina, Tripon Florin, Bănescu Claudia   +2 more
doaj   +1 more source

Dental management of a pediatric patient with progressive familial intrahepatic cholestasis having dental anomalies: a case report and brief review of the literature

BMC Oral Health, 2023
Background Progressive familial intrahepatic cholestasis is a heterogeneous group of disorders, leading to intrahepatic cholestasis, with the possibility of chronic liver failure and biliary cirrhosis.
Mina Yazdizadeh, Maryam Sharifi, Arefeh Torabi Parizi, Firoozeh Alipour, Maryam Ghasempuor, Elham Zanguei, Maryam Yazdizadeh   +6 more
doaj   +1 more source

Computed tomography findings of Crouzon syndrome: A case report

Radiology Case Reports, 2022
Crouzon syndrome is a genetic condition characterized by a premature fusion of skull sutures resulting in head and facial deformities. Crouzon syndrome is usually suspected at birth through physical examination or in the antenatal period via ...
Juan Guillermo Arámbula Neira, MD, Valeria del Castillo Herazo, MD, Nury Tatiana Rincón Cuenca, MD, Angélica M. Sanabria Cano, MD, Maryi Fernanda Bermudez Sarmiento, MD, María F. Castro, MD, Andrés Felipe Herrera Ortiz, MD   +6 more
doaj   +1 more source

Mutational patterns in oncogenes and tumour suppressors [PDF]

, 2016
All cancers depend upon mutations in critical genes, which confer a selective advantage to the tumour cell. Knowledge of these mutations is crucial to understanding the biology of cancer initiation and progression, and to the development of targeted ...
Baeissa, Hanadi M, Benstead-Hume, Graeme, Pearl, Frances M G, Richardson, Christopher J   +3 more
core   +1 more source

Pterygoid bone malformation and its limitations on the effectiveness of brachycephalic airway corrective surgery in brachycephalic dogs

Journal of Small Animal Practice, EarlyView.
Objectives This study aimed to examine the association between pterygoid bone medialisation and treatment outcomes after upper airway surgery in three brachycephalic breeds. Materials and Methods Dogs that underwent CT of the head followed by routine surgery for brachycephalic obstructive airway syndrome were recruited in this study.
S. L. Yuen, M. A. Genain, J. F. Ladlow, N.‐C. Liu   +3 more
wiley   +1 more source