Results 191 to 200 of about 12,339,723 (213)

Beyond Simple Mimicry: Next‐Generation Geometric Architectures and Future Paradigms in Small‐Molecule and Macrocyclic Peptidomimetics

open access: yesAngewandte Chemie, Volume 138, Issue 40, 28 September 2026.
Peptide‐to‐Small Molecule Paradigm: Peptidomimetics have evolved from simple mimicry toward drug‐like scaffolds supported by increasing clinical successes. This Perspective highlights the geometric design principles—linear repetition, convergent fusion, and cyclization—defining the next‐generation peptidomimetic architectures capable of targeting ...
Jesang Lee   +5 more
wiley   +1 more source

Distinct motors, shared mechanics: unifying principles of microbial gliding. [PDF]

open access: yesJ Bacteriol
Sen S   +4 more
europepmc   +1 more source

Acute and chronic effects of high-intensity interval training on selected exerkine secretion in health, disease, and aging: a systematic review. [PDF]

open access: yesFront Physiol
Jost Z   +8 more
europepmc   +1 more source

Preliminary Research of Crank-Group Driving Mechanism

Applied Mechanics and Materials, 2012
To drive multiple parallel-axis to rotate synchronously,this paper put forward a kind of new transmission mechanism——crank-group driving mechanism, introduced the concept of it and its working principles,and demonstrated the feasibility of its movement .
Ju Jiang Cao, Yu Qi Wang, Ji Wei Sun
exaly   +5 more sources

Dynamic analysis of a slider–crank mechanism with eccentric connector and planetary gears

open access: yesMechanism and Machine Theory, 2007
In this study, the kinematic and dynamic analysis of a modified slider-crank mechanism which has an additional eccentric link between connecting rod and crank pin, as distinct from a conventional mechanism, are presented.
Selçuk Erkaya
exaly   +2 more sources

Study on the Basic Configurations of Crank-Group Driving Mechanism

Applied Mechanics and Materials, 2012
On the basis of parallelogram linkage, this paper introduced the working principles of a kind of new transmission mechanism:crank-group driving mechanism, its three basic configurations and their advantages and dis-advantages.
Ju Jiang Cao, Yu Qi Wang
openaire   +1 more source

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