Results 261 to 270 of about 635,017 (399)

Recent Advances in Enzymes and Chemoenzymatic Synthesis of Tetrasaccharide Linkage Region of Proteoglycans

open access: yesChemBioChem, Accepted Article.
Proteoglycans (PGs) play roles in many important biological events including growth factor signaling, wound repair, blood coagulation, brain development, and neural stem cell migration. As the glycosaminoglycan chain of PGs is attached to the core protein through a tetrasaccharide linkage region, it is important to decipher the intricate control of the
Po-han Lin, Xuefei Huang
wiley   +1 more source

Engineering and Structural Elucidation of a Sac7d‐Derived IgG Fc‐Specific Affitin and Its Application for the Light‐Controlled Affinity Purification of Antibodies

open access: yesChemBioChem, EarlyView.
An affitin derived from the Sac7d scaffold enables the light‐controlled affinity purification of antibodies under physiological conditions, thus overcoming limitations of protein A chromatography. X‐ray crystallographic analysis and affinity measurements reveal complex formation with Fc at the CH2/CH3 junction, similar to protein A/G and FnRn. Combined
Felix Veitl   +7 more
wiley   +1 more source

Insights into the Mechanism of a Vanadium Bromoperoxidase from the Marine Macro‐Algae Corallina pilulifera for Biocatalytic Halogenation

open access: yesChemCatChem, EarlyView.
A study of crystallographic complexes obtained from vanadium haloperoxidase enzymes can determine key amino acids, leucine, and phenylalanine, that change their structural orientation to allow either chloride or bromide to bind to the enzymes active site, thereby determining halide specificity.
Daniel E. Mitchell   +3 more
wiley   +1 more source

Home - About - Disclaimer - Privacy