Results 31 to 40 of about 102,117 (311)

Hybrid random utility-random regret model in the presence of preference heterogeneity, modeling drivers’ actions

open access: yesFrontiers in Built Environment, 2022
Despite the importance of drivers’ actions and behaviors, the underlying factors to those actions have not received adequate attention. Understanding the factors contributing to various drivers’ actions before crashes could help policy makers to take ...
Mahdi Rezapour, Khaled Ksaibati
doaj   +1 more source

Using Artificial Neural Network to Destroy the Process of Traffic Accident Victims in Yazd Province

open access: yesHealth in Emergencies & Disasters Quarterly, 2021
Background: Road accidents are among the most important causes of death and severe personal and financial injuries. Also, its profound social, cultural, and economic effects threaten human societies.
Mohammad Reza Omidi   +2 more
doaj  

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Crashworthiness of a type 228M rail vehicle

open access: yesPojazdy Szynowe, 2022
This article presents rail vehicles crashworthiness issues based on the design of the 228M type light railcar. Meeting the requirements of the standard requires the application of appropriate components dedicated to energy absorption and ensuring ...
Dawid Witkowski   +2 more
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Identification and Prioritization of Hazardous Road Locations by Segmentation and Data Envelopment Analysis Approach

open access: yesPromet (Zagreb), 2013
The aim of the present study is the representation of a method to identify and prioritize accident-prone sections (APSs) based upon efficiency concept to emphasize accidents with regard to traffic, geometric and environmental circumstances of road which ...
Aliasghar Sadeghi   +2 more
doaj   +1 more source

CRITICAL CRASHES? [PDF]

open access: yesInternational Journal of Modern Physics C, 1999
In this short note, we discuss recent attempts to describe pre-crash market dynamics with analogies from the theory of critical phenomena.
openaire   +2 more sources

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Crash typology of professional cycling crashes

open access: yesAccident Analysis & Prevention
Mild traumatic brain injury (mTBI) is a frequent but underreported consequence of professional cycling crashes, yet current helmet testing standards primarily simulate head-first impacts, and their representation of real-world head impact scenarios is unclear.
Benjamin P. Krbavac   +5 more
openaire   +2 more sources

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

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