Results 101 to 110 of about 15,423,402 (220)

Accessing intractable, phosphorylated intrinsically disordered proteins via a protease‐cleavable inclusion body tag

Protein Science, Volume 35, Issue 4, April 2026.
Abstract Phosphorylated intrinsically disordered proteins (IDPs), such as Bcl2‐associated agonist of cell death (BAD) and Tau, play critical roles in apoptosis and neurodegeneration, yet their instability during recombinant expression due to degradation, aggregation, and dephosphorylation, has limited structural and mechanistic studies.
Cat Hoang Vesely, Stanislau Stanisheuski, Edward Lien, Patrick Reardon, Peter J. Chung, Ryan A. Mehl, Richard B. Cooley   +6 more
wiley   +1 more source

Healthcare Professional Survey on Complementary Feeding and Allergy Prevention in High‐ Versus Low‐Risk Infants: An EAACI Task Force Report

Allergy, Volume 81, Issue 4, Page 977-999, April 2026.
ABSTRACT Complementary feeding (CF) influences infants' long‐term dietary preferences, growth, and food allergy (FA) risk. However, guidance given to families and the implementation of FA prevention guidelines by healthcare professionals (HCPs) remain unclear.
Emilia Vassilopoulou, Sophia Tsabouri, Stefania Arasi, Anna Comotti, Gregorio Paolo Milani, Klaudia Ryczaj, Carlo Agostoni, Ioannis Pagkalos, Berber Vlieg‐Boerstra, Chrystopherson Gengyny Caballero‐Lopez, Gavriela Feketea, Anna Nowak‐Wegrzyn, Susanne Halken, Burcin Beken, Montserrat Alvaro‐Lozano, Ines Padua, Mattia Giovannini, George Du Toit, Alberto Alvarez‐Perea, Roberto Berni Canani, Diego Peroni, Marina Pérez‐Gordo, Mohamed H. Shamji, Ludger Klimek, Ioana Agache, Elena Camelia Berghea, Franziska Roth‐Walter, Cevdet Ozdemir, Peter Smith, Liam O’ Mahony, Rosan W. Meyer, Carina Venter   +31 more
wiley   +1 more source

Interactive online calculator for estimation of muscle and hepatic insulin sensitivity in adults with Type 1 diabetes using clinical and research biomarkers

Diabetes, Obesity and Metabolism, Volume 28, Issue 4, Page 3238-3244, April 2026.
Abstract Aims Impaired insulin sensitivity is an under‐recognised risk in Type 1 diabetes but is challenging to measure with ‘gold‐standard’ euglycaemic clamps. Adding stable‐isotope glucose distinguishes hepatic and muscle insulin action (assessed by endogenous glucose production [EGP] and glucose infusion rate [GIR], respectively).
Andrzej S. Januszewski, Jennifer R. Snaith, Greg M. Kowalski, Clinton R. Bruce, D. Jane Holmes‐Walker, Alicia J. Jenkins, Jerry R. Greenfield   +6 more
wiley   +1 more source

CRB2 Facilitates Epithelial Ovarian Cancer Progression by Inducing Polarity Changes via Activation of the Wnt/PCP Signalling Pathway

Journal of Cellular and Molecular Medicine, Volume 30, Issue 7, April 2026.
ABSTRACT Ovarian cancer exhibits high molecular heterogeneity and metastatic potential, contributing to its status as a leading cause of gynecologic cancer mortality. Cell polarity is essential in tumorigenesis, yet the role of Crumbs family proteins (CRBs), key regulators of apical–basal polarity, in epithelial ovarian cancer (EOC) remains unclear. In
Chunlin Tao, Shaojing Li, Duohe Sun, Jun Zhou, Yuanping Chen, Rong Zhang, Xiaoge Ni   +6 more
wiley   +1 more source

Effects of short‐term tofogliflozin treatment on the insulin secretory capacity of people with type 2 diabetes: A randomized controlled trial, the TOP‐ELM study

Journal of Diabetes Investigation, Volume 17, Issue 4, Page 627-635, April 2026.
Tofogliflozin was compared with metformin in treatment‐naïve people with type 2 diabetes for 4 weeks. Overall insulin secretory capacity did not improve; however, tofogliflozin was associated with an improved disposition index in individuals with poorer baseline glucose tolerance or greater improvement after treatment.
Maiko Miyamoto, Aika Miya, Akinobu Nakamura, Yuka Takahashi, Yuki Yamauchi, Shingo Yanagiya, Takahiro Takase, Mayuko Ono, Kiyohiko Takahashi, Kazufumi Okada, Hiraku Kameda, Kyu Yong Cho, Tatsuya Atsumi, on behalf of TOP‐ELM study group, Maiko Miyamoto, Aika Miya, Akinobu Nakamura, Hiraku Kameda, Kyu Yong Cho, Tatsuya Atsumi, Kazufumi Okada, Rimi Izumihara, Yuki Oe, Takahiro Takase, So Nagai, Akihiro Takahashi, Yuka Takahashi, Yuki Yamauchi, Hiromichi Kijima, Shinji Taneda, Jun Takeuchi, Kei Yokozeki, Saki Kuwabara, Yoshiaki Arimura, Shinichiro Kawata, Tomonori Sekizaki, Yuki Yamauchi, Shingo Yanagiya, Mayuko Ono, Kiyohiko Takahashi   +39 more
wiley   +1 more source

Monetary Policy, Global Liquidity and Commodity Price Dynamics [PDF]

This paper examines the interactions between money, interest rates, goods and commodity prices at a global level. For this purpose, we aggregate data for major OECD countries and follow the Johansen/Juselius cointegrated VAR approach. Our empirical model
Ansgar Belke, Ingo G. Bordon, Torben W. Hendricks   +2 more
core  

The Monetary Policy–Commodities Nexus: A Survey

Journal of Economic Surveys, Volume 40, Issue 2, Page 1050-1082, April 2026.
ABSTRACT This survey synthesizes evidence on the bidirectional links between commodity markets and monetary policy. On the commodities‐to‐policy side, we review how shocks to energy, food, and metals pass through to inflation, inflation expectations, economic activity, and financial stability in state‐dependent ways that vary by shock type, exposure ...
Martin T. Bohl, Niklas Humann, Pierre L. Siklos   +2 more
wiley   +1 more source

EEG Brain Rhythms During Resting‐State Wakefulness and Sleep in Elderly Expert Meditators

Journal of Sleep Research, Volume 35, Issue 2, April 2026.
Compared to controls, elderly expert meditators exhibited (1) more preserved resting‐state brain activity, (2) less altered sleep architecture, and (3) EEG features indicative of heightened cognitive states during NREM sleep. Importantly, several of the metrics that differed between groups also showed consistent correlations with meditation expertise ...
Pierre Champetier, Anaïs Hamel, Claire André, Valentin Ourry, Tristan Lacroix, Stéphane Rehel, Léa Chauveau, Sacha Haudry, Françoise Bertran, Vincent de la Sayette, Denis Vivien, Gaël Chételat, Antoine Lutz, Géraldine Rauchs, Medit‐Ageing Research Group, Alexandre Bejanin, Anne Chocat, Fabienne Collette, Sophie Dautricourt, Robin De Flores, Marion Delarue, Harriet Demnitz‐King, Hélène Espérou, Séverine Fauvel, Francesca Felisatti, Eglantine Ferrand Devouge, Eric Frison, Julie Gonneaud, Oriane Hébert, Olga Klimecki, Elizabeth Kuhn, Brigitte Landeau, Valérie Lefranc, Natalie Marchant, Florence Mezenge, Cassandre Palix, Anne Quillard, Florence Requier, Daniel Roquet, Edelweiss Touron, Anne‐Laure Turpin, Patrik Vuilleumier, Tim Whitfield, Miranka Wirth   +43 more
wiley   +1 more source

The Effect of Monetary Policy on Commodity Prices: Disentangling the Evidence for Individual Prices [PDF]

In this paper we study the effect of monetary policy shocks on commodity prices. While most of the literature has found that expansionary shocks have a positive effect on aggregate price indices, we study the effect on individual prices of a sample of ...
Carolina Arteaga Cabrales, Jair Ojeda Joya, Joan Camilo Granados Castro   +2 more
core  

What is hidden in the Fed's model? The second approximation [PDF]

There are a lot of approaches for estimation of the equity market attractiveness. Fed's model has received a wide prevalence. However this model has a number of essential restrictions.
Dmitry Baryshevsky
core